Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431607 | 0.85 | SMN1; SMN2 (0.46) | HPGDTSHRRAB9AALDH1A1KCNJ11 | |
| SCHEMBL3420846 | 0.78 | NR1H2 (0.43) | RAB9APDK1PDK2PDK3PDK4 | |
| SCHEMBL3419156 | 0.76 | PDK1 (0.54) | HSD11B1RAB9APDK1PDK2PDK3 | |
| SCHEMBL20956394 | 0.76 | PDK1 (0.54) | HSD11B1RAB9APDK1PDK2PDK3 | |
| SCHEMBL19180948 | 0.76 | PDK1 (0.54) | HSD11B1RAB9APDK1PDK2PDK3 | |
| SCHEMBL1827810 | 0.74 | GAA (0.45) | TSHRRAB9AABCC9ABCC8KCNJ11 | |
| SCHEMBL2259335 | 0.74 | PTGS1 (0.55) | RAB9AALDH1A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL17286709 | 0.74 | ESR1 (0.45) | HSD11B1 | |
| SCHEMBL1813435 | 0.74 | HSD11B1 (0.37) | HSD11B1 | |
| SCHEMBL2094230 | 0.73 | ALDH1A1 (0.65) | HPGDTSHRALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015355-A2 | NOVEL ACYLAMINOBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-02-11 | — | — | WO | disclosed |