Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1813928 | 0.81 | PTGS1 (0.51) | GAAABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3420100 | 0.78 | HSD11B1 (0.40) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL3431607 | 0.78 | SMN1; SMN2 (0.46) | NR1H2KCNJ11MEN1KMT2ARAB9A | |
| SCHEMBL1810895 | 0.77 | ABCC9 (0.57) | ABCC9ABCC8KCNJ11KCNJ8MEN1 | |
| SCHEMBL1813640 | 0.77 | NR1H2 (0.43) | NR1H2GAAMEN1KMT2AHTT | |
| SCHEMBL3465464 | 0.76 | KCNK3 (0.56) | MEN1KMT2AHTTMAPTRAB9A | |
| SCHEMBL5865852 | 0.75 | TSHR (0.52) | NR1H2MAPTNR1I2LMNANPSR1 | |
| SCHEMBL1812412 | 0.75 | NR1H2 (0.43) | NR1H2PDK1PDK2PDK3PDK4 | |
| SCHEMBL1812445 | 0.74 | TDP1 (0.44) | NR1H2PDK1PDK2PDK3PDK4 | |
| SCHEMBL16799985 | 0.73 | SMN1; SMN2 (0.66) | NR1H2PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015355-A2 | NOVEL ACYLAMINOBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-02-11 | — | — | WO | disclosed |