SCHEMBL3420534

SCHEMBL3420534

OC1OCc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
NISCH Q9Y2I1 1/20 0.39
HTR2A P28223 1/20 0.37
SLC6A2 P23975 9/20 0.36
CYP2D6 P10635 8/20 0.36
SLC6A4 P31645 7/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ACP3 P15309 1/20 0.35
LMNA P02545 1/20 0.35
SLC6A3 Q01959 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24999225 1.00 MAOA (0.41) MAOAMAOBNISCHHTR2ASLC6A2
Hydrochloric Acid SCHEMBL27782030 0.98 MAOA (0.40) MAOAMAOBNISCHHTR2ASLC6A2
SCHEMBL23377295 0.98 MAOA (0.40) MAOAMAOBNISCHHTR2ASLC6A2
SCHEMBL7343966 0.78 ALDH1A1 (0.44) MAOAMAOBHTR2ACYP2D6RAB9A
SCHEMBL30587236 0.78 ALDH1A1 (0.44) MAOAMAOBHTR2ACYP2D6RAB9A
SCHEMBL16534913 0.78 HSD17B10 (0.41) MAOAMAOBSMN1; SMN2LMNA
SCHEMBL27415175 0.76 HTR2A (0.39) NISCHHTR2ASLC6A2CYP2D6SLC6A4
SCHEMBL19810459 0.75 SLC6A2 (0.38) MAOAMAOBNISCHSLC6A2CYP2D6
SCHEMBL11419089 0.73 SLC6A2 (0.37) NISCHHTR2ASLC6A2CYP2D6SLC6A4
SCHEMBL22731139 0.73 HTR2A (0.37) NISCHHTR2ASLC6A2CYP2D6SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022253252-A1 HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS SILEXON BIOTECH CO., LTD. (CN) 2022-12-08 WO claimed
CN-114989417-A Alkyl-polyphenol 2D Janus nanosheet and Pickering emulsion as well as preparation method and application thereof 石河子大学 2022-09-02 CN claimed
CN-113122062-A Quantum dot ink and preparation method of quantum dot film TCL集团股份有限公司 2021-07-16 CN claimed
US-9944663-B2 Process for preparing substituted pentacenes MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2018-04-17 US claimed
US-20120305854-A1 PROCESS FOR PREPARING SUBSTITUTED PENTACENES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-12-06 US claimed
US-8318048-B2 Process for preparing substituted pentacenes MERCK PATENT GMBH (DE) 2012-11-27 US claimed
EP-2134725-B1 PROCESS FOR PREPARING SUBSTITUTED PENTACENES MERCK PATENT GMBH (DE) 2012-07-04 EP claimed
US-20100127220-A1 Process for Preparing Substituted Pentacenes MERCK PATENT GMBH (DE) 2010-05-27 US claimed
EP-2134725-A1 PROCESS FOR PREPARING SUBSTITUTED PENTACENES Merck Patent GmbH (DE) 2009-12-23 EP claimed
WO-2008128618-A1 PROCESS FOR PREPARING SUBSTITUTED PENTACENES MERCK PATENT GMBH (DE) 2008-10-30 WO claimed
EP-4296365-A2 PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID Visolis, Inc. (US) 2023-12-27 EP disclosed
EP-3224368-B1 PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID VISOLIS INC (US) 2023-10-25 EP disclosed
US-20230045245-A1 HETEROCYCLIC COMPOUND OR SALT THEREOF, ACTIVE MATERIAL, ELECTROLYTIC SOLUTION AND REDOX FLOW BATTERY NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2023-02-09 US disclosed
WO-2022253252-A1 HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS SILEXON BIOTECH CO., LTD. (CN) 2022-12-08 WO disclosed
CN-115215995-A Phosphorus-nitrogen-containing hindered phenol-based flame retardant and preparation method and application thereof 东莞理工学院 2022-10-21 CN disclosed
EP-0737189-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CNS AND CARDIOVASCULAR DISORDERS PHARMACIA & UPJOHN COMPANY (US) 1996-10-16 EP disclosed
WO-1995018118-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CNS AND CARDIOVASCULAR DISORDERS THE UPJOHN COMPANY (US) 1995-07-06 WO disclosed
EP-0022875-B1 PRESSURE-SENSITIVE RECORDING MATERIAL MISHIMA PAPER CO. LTD (JP) 1985-03-13 EP disclosed
US-4339143-A Pressure-sensitive recording material MISHIMA PAPER CO., LTD. (JP) 1982-07-13 US disclosed
EP-0022875-A1 PRESSURE-SENSITIVE RECORDING MATERIAL MISHIMA PAPER CO. LTD (JP) 1981-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100127220-A1 Process for Preparing Substituted Pentacenes FES, PFAS, SLC46A1 MAOA 2348/4885MAOB 3180/4885NISCH 1047/4885
US-20120305854-A1 PROCESS FOR PREPARING SUBSTITUTED PENTACENES FES, PFAS, SLC46A1 MAOA 2348/4885MAOB 3180/4885NISCH 1047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.