Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7182270 | 0.91 | PLK1 (0.47) | ALDH1A1POLBPLK1THRBCNR2 | |
| SCHEMBL22499724 | 0.87 | PLK1 (0.40) | ALDH1A1GAAKDM4EPOLBCTDSP1 | |
| SCHEMBL11897801 | 0.79 | ALDH1A1 (0.47) | ALDH1A1GAANPC1FEN1 | |
| SCHEMBL10527004 | 0.78 | TAS1R3 (0.44) | POLBPLK1NPC1MAPTRAB9A | |
| SCHEMBL9515898 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KDM4ENPC1MAPTSENP8 | |
| SCHEMBL57873 | 0.72 | GAA (0.43) | ALDH1A1GAAKDM4EPOLBCTDSP1 | |
| SCHEMBL21694085 | 0.72 | PLK1 (0.40) | ALDH1A1GAAKDM4EPOLBCTDSP1 | |
| SCHEMBL4264438 | 0.72 | GAA (0.43) | ALDH1A1GAAKDM4EPOLBCTDSP1 | |
| SCHEMBL7607626 | 0.69 | ITGB1 (0.51) | ALDH1A1GAAKDM4EPOLBCTDSP1 | |
| SCHEMBL7759428 | 0.69 | GPBAR1 (0.44) | ALDH1A1GAAKDM4EPOLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002244-B1 | METHOD OF PREPARING FOLDABLE HIGH REFRACTIVE INDEX ACRYLIC OPHTHALMIC DEVICE MATERIALS | ALCON LAB INC (US) | 2003-02-26 | — | — | EP | claimed |
| EP-1002243-B1 | METHOD OF PREPARING FOLDABLE HYDROPHILIC OPHTHALMIC DEVICE MATERIALS | ALCON LAB INC (US) | 2001-11-14 | — | — | EP | claimed |
| EP-0325266-B1 | DENTAL MATTER | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) | 1993-08-11 | — | — | EP | claimed |
| EP-2931790-B1 | ACTINICALLY-CROSSLINKABLE AMPHIPHILIC PREPOLYMERS | NOVARTIS AG (CH) | 2017-02-15 | — | — | EP | disclosed |
| EP-2510052-B1 | A SILICONE HYDROGEL LENS WITH A COVALENTLY ATTACHED COATING | NOVARTIS AG (CH) | 2017-02-08 | — | — | EP | disclosed |
| EP-2233538-B1 | Photocurable composition | FUJIFILM CORP (JP) | 2012-06-06 | — | — | EP | disclosed |
| EP-2233538-A1 | Photocurable composition | Fujifilm Corporation (JP) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009054621-A2 | THE COMPOSITION OF DECOLORABLE INK AND DECOLORING METHOD | HAN JONG-SOO (KR) | 2009-04-30 | — | — | WO | disclosed |
| US-20050261393-A1 | Utilization of polyacids having a tight molar mass distribution | 3M ESPE (DE) | 2005-11-24 | — | — | US | disclosed |
| EP-1066335-B1 | SULPHUR PRODUCTS FOR ADDING A POLYTHIOL ON A NORBORNENE DERIVATIVE, PREPARATION METHOD AND USE FOR OBTAINING RADICAL CROSS-LINKING PRODUCTS | CRAY VALLEY SA (FR) | 2003-07-02 | — | — | EP | disclosed |
| EP-1066335-A1 | SULPHUR PRODUCTS FOR ADDING A POLYTHIOL ON A NORBORNENE DERIVATIVE, PREPARATION METHOD AND USE FOR OBTAINING RADICAL CROSS-LINKING PRODUCTS | CRAY VALLEY SA (FR) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051663-A1 | SULPHUR PRODUCTS FOR ADDING A POLYTHIOL ON A NORBORNENE DERIVATIVE, PREPARATION METHOD AND USE FOR OBTAINING RADICAL CROSS-LINKING PRODUCTS | CRAY VALLEY S.A. (FR) | 1999-10-14 | — | — | WO | disclosed |