Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420869 | 0.91 | ALDH1A1 (0.41) | PLK1ALDH1A1THRBPOLBCNR2 | |
| SCHEMBL22499724 | 0.78 | PLK1 (0.40) | PLK1ALDH1A1THRBPOLBCNR2 | |
| SCHEMBL11897801 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGD | |
| SCHEMBL10527004 | 0.75 | TAS1R3 (0.44) | PLK1POLB | |
| SCHEMBL9515898 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HPGD | |
| SCHEMBL76776 | 0.73 | PLK1 (0.49) | PLK1ALDH1A1HPGDHSD17B10AKR1C2 | |
| Decane SCHEMBL8529247 | 0.72 | PLK1 (0.44) | PLK1ALDH1A1HPGDCNR2 | |
| SCHEMBL15824404 | 0.70 | PLK1 (0.49) | PLK1ALDH1A1HPGDHSD17B10AKR1C2 | |
| SCHEMBL7604301 | 0.70 | NPC1 (0.52) | PLK1ALDH1A1HPGDTRPV1POLB | |
| SCHEMBL4331990 | 0.70 | PLK1 (0.42) | PLK1ALDH1A1HPGDEP300KAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002244-B1 | METHOD OF PREPARING FOLDABLE HIGH REFRACTIVE INDEX ACRYLIC OPHTHALMIC DEVICE MATERIALS | ALCON LAB INC (US) | 2003-02-26 | — | — | EP | claimed |
| EP-1002243-B1 | METHOD OF PREPARING FOLDABLE HYDROPHILIC OPHTHALMIC DEVICE MATERIALS | ALCON LAB INC (US) | 2001-11-14 | — | — | EP | claimed |
| EP-3724699-B1 | METHOD FOR PRODUCING MPS-COMPATIBLE WATER GRADIENT CONTACT LENSES | ALCON INC (CH) | 2023-07-26 | — | — | EP | disclosed |
| EP-3634733-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2020-04-15 | — | — | EP | disclosed |
| WO-2018224976-A1 | SILICONE HYDROGEL CONTACT LENSES | NOVARTIS AG (CH) | 2018-12-13 | — | — | WO | disclosed |