Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | CDC42 | P60953 | 1/20 | 0.49 |
| ▸ | RAC1 | P63000 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30577888 | 1.00 | KDM4E (0.69) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL9301384 | 0.85 | KDM4E (0.62) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL11856961 | 0.85 | KDM4E (0.49) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL562943 | 0.83 | CA1 (0.63) | CYP1A2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11780406 | 0.82 | KDM4E (0.73) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL14339888 | 0.82 | KDM4E (0.58) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL34463427 | 0.82 | KDM4E (1.00) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL8132 | 0.82 | KDM4E (1.00) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL6152954 | 0.81 | CES2 (0.65) | ALDH1A1MEN1KMT2ANPC1TSHR | |
| Hydrochloric Acid SCHEMBL3541422 | 0.80 | KDM4E (0.96) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116732537-A | New synthesis method of naproxen | 上海颐碳化学科技有限公司 | 2023-09-12 | — | — | CN | claimed |
| EP-0954375-A4 | NOVEL SUPPORTED CATALYSTS | SETON HALL UNIVERSITY (US) | 2000-06-21 | — | — | EP | claimed |
| US-6005148-A | COMPRISING SUPPORT, ANCHORING AGENT SUCH AS HETEROPOLY ACID OR ANION, AND METAL COMPLEX USEFUL IN HYDROGENATION OF SUBSTITUTED UNSATURATED ACIDS AND ESTERS | SETON HALL UNIVERSITY (US) | 1999-12-21 | — | — | US | claimed |
| WO-1999064154-A1 | POLY-OXYANIONS AS ANCHORING AGENTS FOR METAL COMPLEXES | SETON HALL UNIVERSITY (US) | 1999-12-16 | — | — | WO | claimed |
| US-5990318-A | Soluble polyester-supported chiral phosphines | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 1999-11-23 | — | — | US | claimed |
| EP-0954375-A1 | NOVEL SUPPORTED CATALYSTS | Seton Hall University (US) | 1999-11-10 | — | — | EP | claimed |
| WO-1998028074-A1 | NOVEL SUPPORTED CATALYSTS | SETON HALL UNIVERSITY (US) | 1998-07-02 | — | — | WO | claimed |
| EP-0433424-B1 | IMPROVED ASYMMETRIC CATALYTIC HYDROGENATION OF ALPHA-ARYLPROPENOIC ACIDS | MONSANTO CO (US) | 1995-05-24 | — | — | EP | claimed |
| EP-0633238-A2 | Asymmetric catalytic hydrogenation of alpha-arylpropenoic acids | MONSANTO COMPANY (US) | 1995-01-11 | — | — | EP | claimed |
| EP-0561908-A1 | METHOD FOR PREPARING $g(a)-ARYLPROPIONIC ACIDS | MONSANTO COMPANY (US) | 1993-09-29 | — | — | EP | claimed |
| US-5233084-A | Electrochemical carboxylation; dehydration, catalytic asymetric hydrogenation | MONSANTO COMPANY (US) | 1993-08-03 | — | — | US | claimed |
| US-5202474-A | Forming alpha-arylpropionic acid by using a coordination catalysts | MONSANTO COMPANY (US) | 1993-04-13 | — | — | US | claimed |
| WO-1992009552-A1 | METHOD FOR PREPARING α-ARYLPROPIONIC ACIDS | MONSANTO COMPANY (US) | 1992-06-11 | — | — | WO | claimed |
| EP-0275354-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE ARYLACETIC ACID DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-10-16 | — | — | EP | claimed |
| EP-0433424-A1 | IMPROVED ASYMMETRIC CATALYTIC HYDROGENATION OF ALPHA-ARYLPROPENOIC ACIDS. | MONSANTO CO (US) | 1991-06-26 | — | — | EP | claimed |
| US-4994607-A | Using a rhodium or ruthenium coordination complex of a chiral phosphine compound | MONSANTO COMPANY (US) | 1991-02-19 | — | — | US | claimed |
| WO-1990015790-A1 | IMPROVED ASYMMETRIC CATALYTIC HYDROGENATION OF ALPHA-ARYLPROPENOIC ACIDS | MONSANTO COMPANY (US) | 1990-12-27 | — | — | WO | claimed |
| US-4762948-A | USING METALLOCENYL PHOSPHINE REDUCING AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-09 | — | — | US | claimed |
| US-4239914-A | Process for preparing 2-(6'-methoxy-2'-naphthyl)-propionic acid | MONTEDISON S.P.A. (IT) | 1980-12-16 | — | — | US | claimed |
| US-3994968-A | 2-(5'-Halo-6'-methoxynaphth-2'-yl)-acrylic acid | SYNTEX CORPORATION (PM) | 1976-11-30 | — | — | US | claimed |