SCHEMBL3422016

SCHEMBL3422016

Nc1ccc(CNc2ccc(NCc3ccc(N)cc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
MAPT P10636 4/20 0.50
ALDH1A1 P00352 3/20 0.50
GAA P10253 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
POLB P06746 2/20 0.50
HPGD P15428 2/20 0.50
ALOX15 P16050 2/20 0.50
MAPK1 P28482 2/20 0.50
CASP1 P29466 2/20 0.50
BLM P54132 2/20 0.50
HSD17B10 Q99714 2/20 0.50
AGER Q15109 1/20 0.50
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
KDM4E B2RXH2 1/20 0.50
HSP90AA1 P07900 1/20 0.50
HSP90AB1 P08238 1/20 0.50
THRB P10828 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL455536 1.00 MEN1 (0.50) MEN1KMT2AMAPTALDH1A1GAA
SCHEMBL5154356 1.00 MEN1 (0.50) MEN1KMT2AMAPTALDH1A1GAA
Hydrochloric Acid SCHEMBL4949253 0.98 MAOA (0.48) MEN1KMT2AMAPTALDH1A1GAA
Hydrochloric Acid SCHEMBL2985269 0.98 MAOA (0.48) MEN1KMT2AMAPTALDH1A1GAA
SCHEMBL14071631 0.93 FFAR1 (0.51) MEN1KMT2AMAPTALDH1A1GAA
SCHEMBL13971150 0.93 ALDH1A1 (0.61) MEN1KMT2AMAPTALDH1A1GAA
SCHEMBL11936055 0.89 LMNA (0.53) MAPTGAAL3MBTL1ALOX15MAOB
SCHEMBL11935862 0.89 MEN1 (0.61) MEN1KMT2AMAPTALDH1A1L3MBTL1
SCHEMBL15996872 0.89 LMNA (0.53) MAPTGAAL3MBTL1ALOX15MAOB
SCHEMBL11935902 0.89 MAOA (0.43) MEN1KMT2AMAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4526835-A Prepreg resin sheets formed by impregnating reinforcing substrate with curable polyimide, binding laminated sheets with heat, pressure HITACHI, LTD. (JP) 1985-07-02 US claimed
US-4486583-A MOLDING MATERIALS, COATINGS HITACHI, LTD. (JP) 1984-12-04 US claimed
US-4393188-A PRINTED CIRCUITS HITACHI CHEMICAL COMPANY, LTD. (JP) 1983-07-12 US claimed
US-4283522-A BY HEATING WITH A DIAMINE HITACHI CHEMICAL COMPANY, LTD. (JP) 1981-08-11 US claimed
CN-113784999-B Fluorine-containing epoxy resin for electrical material and method for producing same 大金工业株式会社 2024-09-20 CN disclosed
US-11965060-B2 Fluorine-containing epoxy resin for electrical materials and method for manufacturing same DAIKIN INDUSTRIES, LTD. (JP) 2024-04-23 US disclosed
US-20220298294-A1 COMPOSITION, CURABLE COMPOSITION, AND CURED PRODUCT DAIKIN INDUSTRIES, LTD. (JP) 2022-09-22 US disclosed
EP-4053214-A1 COMPOSITION, CURABLE COMPOSITION, AND CURED PRODUCT Daikin Industries, Ltd. (JP) 2022-09-07 EP disclosed
CN-114829496-A Composition, curable composition, and cured product 大金工业株式会社 2022-07-29 CN disclosed
US-20220081507-A1 FLUORINE-CONTAINING EPOXY RESIN FOR ELECTRICAL MATERIALS AND METHOD FOR MANUFACTURING SAME DAIKIN INDUSTRIES, LTD. (JP) 2022-03-17 US disclosed
EP-3960788-A1 FLUORINE-CONTAINING EPOXY RESIN FOR ELECTRICAL MATERIALS AND METHOD FOR MANUFACTURING SAME DAIKIN INDUSTRIES, LTD. (JP) 2022-03-02 EP disclosed
US-10870724-B2 High heat monomers and methods of use thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-12-22 US disclosed
US-4400438-A MALEIMIDE RESING AND HALOGENATED DIPHENYL ETHER HITACHI CHEMICAL COMPANY, LTD. (JP) 1983-08-23 US disclosed
US-4393188-A PRINTED CIRCUITS HITACHI CHEMICAL COMPANY, LTD. (JP) 1983-07-12 US disclosed
EP-0078039-A1 Thermosetting resin composition, prepolymer thereof and cured article thereof Hitachi, Ltd. (JP) 1983-05-04 EP disclosed
EP-0059434-A2 Multi-layer printed circuit board and process for production thereof Hitachi, Ltd. (JP) 1982-09-08 EP disclosed
US-4346206-A Imide prepolymer from reaction of epoxy compound with bis-imide/diamine reaction mixture HITACHI CHEMICAL COMPANY, LTD. (JP) 1982-08-24 US disclosed
US-4296219-A Bismide-ether compounds, compositions thereof, and method of producing same HITACHI, LTD. (JP) 1981-10-20 US disclosed
US-4283522-A BY HEATING WITH A DIAMINE HITACHI CHEMICAL COMPANY, LTD. (JP) 1981-08-11 US disclosed
EP-0004592-A1 Bisimide-ether compounds, compositions containing these compounds, and a method for their production Hitachi, Ltd. (JP) 1979-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10870724-B2 High heat monomers and methods of use thereof HSP90AA1, HSP90AB1, EPHX2 MEN1 3092/4885KMT2A 4211/4885MAPT 969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.