Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | AGER | Q15109 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455536 | 1.00 | MEN1 (0.50) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL3422016 | 1.00 | MEN1 (0.50) | MEN1KMT2AMAPTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL4949253 | 0.98 | MAOA (0.48) | MEN1KMT2AMAPTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL2985269 | 0.98 | MAOA (0.48) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL14071631 | 0.93 | FFAR1 (0.51) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL13971150 | 0.93 | ALDH1A1 (0.61) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11936055 | 0.89 | LMNA (0.53) | MAPTGAAL3MBTL1ALOX15MAOB | |
| SCHEMBL11935862 | 0.89 | MEN1 (0.61) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL15996872 | 0.89 | LMNA (0.53) | MAPTGAAL3MBTL1ALOX15MAOB | |
| SCHEMBL11935902 | 0.89 | MAOA (0.43) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7422609-B2 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2008-09-09 | — | — | US | disclosed |
| US-7422609-B2 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2008-09-09 | — | — | US | disclosed |
| US-20070011824-A1 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011824-A1 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1739085-A1 | Cosmetic composition containing a double para-phenylenediamines joined by an aromatic group and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739085-A1 | Cosmetic composition containing a double para-phenylenediamines joined by an aromatic group and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739085-A1 | Cosmetic composition containing a double para-phenylenediamines joined by an aromatic group and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011824-A1 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | KRT18, CDC73, JUP | MEN1 4539/4885KMT2A 1117/4885MAPT 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.