Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 13/20 | 0.67 |
| ▸ | DDO | Q99489 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16767851 | 0.80 | DAO (1.00) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3418547 | 0.80 | DAO (0.61) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3422279 | 0.76 | DAO (0.61) | DAODDO | |
| SCHEMBL3423807 | 0.76 | DAO (1.00) | DAODDO | |
| SCHEMBL3432410 | 0.75 | DAO (0.58) | DAODDOLMNA | |
| SCHEMBL3395093 | 0.73 | DAO (0.67) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL11740631 | 0.73 | KDM4E (0.51) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3361211 | 0.73 | DAO (0.53) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3432805 | 0.73 | DAO (0.67) | DAODDO | |
| SCHEMBL3425229 | 0.73 | DAO (0.57) | DAODDOGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |