Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734879 | 0.77 | KCNN4 (0.46) | PDK2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL10076748 | 0.76 | ESR1 (0.50) | PDK2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL19002147 | 0.74 | MEN1 (0.52) | PDK2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3423319 | 0.74 | PDK2 (0.50) | PDK2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL29830420 | 0.74 | PDK2 (0.46) | PDK2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL15283116 | 0.74 | DPP4 (0.48) | PDK2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL648491 | 0.73 | IDO1 (0.44) | PDK2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL44942 | 0.73 | KMT2A (0.56) | PDK2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL29355276 | 0.73 | KMT2A (0.56) | PDK2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL18100879 | 0.73 | ESR1 (0.54) | PDK2MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11213550-B2 | Cell preparation for treating cartilage tissue-related disorder | NIPPON SHOKUBAI CO., LTD. (JP) | 2022-01-04 | — | — | US | disclosed |
| US-20190307807-A1 | CELL PREPARATION | NIPPON SHOKUBAI CO., LTD. (JP) | 2019-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11213550-B2 | Cell preparation for treating cartilage tissue-related disorder | COL2A1, MATR3, ADAMTS1 | PDK2 1234/4885MAPT 2431/4885MEN1 3282/4885 |
| US-20190307807-A1 | CELL PREPARATION | COL2A1, MATR3, COL1A1 | PDK2 1275/4885MAPT 2605/4885MEN1 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.