SCHEMBL3423677

SCHEMBL3423677

O=C(Cl)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
HTT P42858 1/20 0.37
THRB P10828 1/20 0.34
USP2 O75604 1/20 0.34
MAPT P10636 1/20 0.34
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5705237 1.00 TSHR (0.38) TSHRKDM4ETDP1L3MBTL1HTT
SCHEMBL10617895 1.00 TSHR (0.38) TSHRKDM4ETDP1L3MBTL1HTT
SCHEMBL7729495 1.00 TSHR (0.38) TSHRKDM4ETDP1L3MBTL1HTT
SCHEMBL2796672 0.91 KDM4E (0.40) TSHRKDM4ETDP1
SCHEMBL7733766 0.90 THRB (0.45) TSHRKDM4ETDP1L3MBTL1HTT
SCHEMBL8103486 0.85 THRB (0.41) TSHRKDM4ETDP1L3MBTL1HTT
SCHEMBL28464094 0.83 THRB (0.32) THRB
SCHEMBL10831355 0.83 THRB (0.32) THRB
SCHEMBL28461375 0.83 THRB (0.32) THRB
SCHEMBL11904370 0.83 THRB (0.46) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820584-A Modified amino resin and preparation method thereof 安徽省海徽化工有限公司 2024-04-05 CN claimed
US-11649202-B2 Fluorinated esters as lubricants for heat transfer fluids MEXICHEM FLUOR S.A. DE C.V. (MX) 2023-05-16 US claimed
CN-113336492-B Durable foam concrete and preparation method thereof 北京慕湖新材料技术有限公司 2021-11-26 CN claimed
CN-113336492-A Durable foam concrete and preparation method thereof 北京慕湖新材料技术有限公司 2021-09-03 CN claimed
US-10131757-B2 Methods for surface modification of materials QED LABS, INC. (US) 2018-11-20 US claimed
US-20170298202-A1 METHODS FOR SURFACE MODIFICATION OF MATERIALS QED LABS INC (US) 2017-10-19 US claimed
US-20170267815-A1 METHODS FOR SURFACE MODIFICATION OF MATERIALS QED LABS, INC. 2017-09-21 US claimed
EP-3386941-B1 COMPOSITION COMPRISING FLUORINATED ESTERS AS LUBRICANTS FOR HEAT TRANSFER FLUIDS MEXICHEM FLUOR SA DE CV (MX) 2024-09-04 EP disclosed
CN-117820584-A Modified amino resin and preparation method thereof 安徽省海徽化工有限公司 2024-04-05 CN disclosed
US-11649202-B2 Fluorinated esters as lubricants for heat transfer fluids MEXICHEM FLUOR S.A. DE C.V. (MX) 2023-05-16 US disclosed
US-20230142258-A1 STAPLE FIBERS CONTAINING RELEASABLE SURFACE MODIFYING MOLECULES QED LABS, INC. 2023-05-11 US disclosed
CN-113336492-B Durable foam concrete and preparation method thereof 北京慕湖新材料技术有限公司 2021-11-26 CN disclosed
CN-113336492-A Durable foam concrete and preparation method thereof 北京慕湖新材料技术有限公司 2021-09-03 CN disclosed
WO-1997026300-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES ELI LILLY AND COMPANY (US) 1997-07-24 WO disclosed
EP-0284081-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1994-08-10 EP disclosed
US-4946771-A POLYMERIC COUPLERS; SHARPNESS, PREVENT MIXING OF COLORS FUJI PHOTO FILM CO., LTD. (JP) 1990-08-07 US disclosed
EP-0284081-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-09-28 EP disclosed
US-4495275-A ANTISTATIC, ANTISTICKING AGENTS;WATER-SOLUBLE OPLYMERS WITH STYRENE MONOMER HAVING A FLUORINE-CONTAINING GROUP FUJI PHOTO FILM CO., LTD. (JP) 1985-01-22 US disclosed
US-4366238-A FLUORINE CONTAINING WATER INSOLUB STYRENIC POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1982-12-28 US disclosed
US-4362812-A BETAINE COPOLYMER FUJI PHOTO FILM CO., LTD. (JP) 1982-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11649202-B2 Fluorinated esters as lubricants for heat transfer fluids F12, MUC1, F13A1 TSHR 2731/4885KDM4E 4663/4885TDP1 3256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.