Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.50 |
| ▸ | DHODH | Q02127 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13433220 | 0.83 | MEN1 (0.56) | PDE10ALMNAKCNA3KMT2AKDM4E | |
| SCHEMBL641899 | 0.80 | PDE10A (0.66) | PDE10ADHODHLMNATSHRKMT2A | |
| SCHEMBL29377848 | 0.80 | PDE10A (0.66) | PDE10ADHODHLMNATSHRKMT2A | |
| SCHEMBL3423756 | 0.79 | DHODH (0.47) | PDE10ADHODHKCNA3TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL9597551 | 0.78 | PDE10A (0.63) | PDE10ADHODHLMNATSHRKMT2A | |
| Iodide SCHEMBL8029601 | 0.78 | PDE10A (0.63) | PDE10ADHODHLMNATSHRKMT2A | |
| Water SCHEMBL2991911 | 0.78 | PDE10A (0.63) | PDE10ADHODHLMNATSHRKMT2A | |
| Iodide SCHEMBL8029606 | 0.78 | PDE10A (0.63) | PDE10ADHODHLMNATSHRKMT2A | |
| Hydrochloric Acid SCHEMBL1603404 | 0.78 | PDE10A (0.63) | PDE10ADHODHLMNATSHRKMT2A | |
| SCHEMBL15263712 | 0.77 | KCNA3 (0.50) | PDE10ADHODHLMNAKCNA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7695980-B2 | Chemiluminescent compounds and their use | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-04-13 | — | — | US | disclosed |
| US-7695980-B2 | Chemiluminescent compounds and their use | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-04-13 | — | — | US | disclosed |
| US-20060199833-A1 | Novel chemiluminescent compounds and their use | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2006-09-07 | — | — | US | disclosed |
| EP-1658495-A1 | NOVEL CHEMILUMINESCENT COMPOUNDS AND THEIR USE | Roche Diagnostics GmbH (DE) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005015214-A1 | NOVEL CHEMILUMINESCENT COMPOUNDS AND THEIR USE | ROCHE DIAGNOSTICS GMBH (DE) | 2005-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199833-A1 | Novel chemiluminescent compounds and their use | LANCL1, LPO, HLCS | PDE10A 234/4885DHODH 1723/4885LMNA 1905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.