SCHEMBL9915565

SCHEMBL9915565

O=C1C=C(O)c2ccccc21

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.74
MAPK1 P28482 4/20 0.74
KDM4E B2RXH2 3/20 0.74
ALDH1A1 P00352 3/20 0.74
CYP3A4 P08684 2/20 0.74
HPGD P15428 2/20 0.74
PTPN22 Q9Y2R2 1/20 0.74
KMT2A Q03164 5/20 0.59
MEN1 O00255 4/20 0.59
PABPC1 P11940 1/20 0.59
RXFP1 Q9HBX9 1/20 0.59
USP2 O75604 2/20 0.52
POLB P06746 2/20 0.52
RECQL P46063 2/20 0.52
CTDSP1 Q9GZU7 1/20 0.52
CDC25B P30305 4/20 0.50
IDO1 P14902 3/20 0.50
MAOA P21397 3/20 0.50
MAOB P27338 2/20 0.50
SNCA P37840 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lawsone SCHEMBL29350263 0.85 MAPT (0.68) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL16541 0.85 MAPT (0.68) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL6849999 0.85 MAPT (0.68) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL5826345 0.85 MAPT (0.68) MAPTMAPK1KDM4EALDH1A1CYP3A4
SCHEMBL342409 0.85 KDM4E (1.00) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL6052663 0.83 MAPT (0.65) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL6052709 0.83 MAPT (0.65) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL6052722 0.83 MAPT (0.65) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL9136705 0.81 MAPT (0.63) MAPTMAPK1KDM4EALDH1A1CYP3A4
SCHEMBL1708417 0.81 MAPT (0.52) MAPTMAPK1KDM4EALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9714356-B2 Black ink composition, ink set, and image forming method FUJIFILM CORPORATION (JP) 2017-07-25 US disclosed
US-9714356-B2 Black ink composition, ink set, and image forming method FUJIFILM CORPORATION (JP) 2017-07-25 US disclosed
US-9614165-B2 Photoelectric conversion element, dye-sensitized solar cell, metal complex dye, dye solution, dye-adsorbed electrode and method of producing dye-sensitized solar cell FUJIFILM CORPORATION (JP) 2017-04-04 US disclosed
US-9614165-B2 Photoelectric conversion element, dye-sensitized solar cell, metal complex dye, dye solution, dye-adsorbed electrode and method of producing dye-sensitized solar cell FUJIFILM CORPORATION (JP) 2017-04-04 US disclosed
US-20150280145-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, DYE-ABSORBED ELECTRODE AND METHOD OF PRODUCING DYE-SENSITIZED SOLAR CELL FUJIFILM CORPORATION (JP) 2015-10-01 US disclosed
US-20150280145-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, DYE-ABSORBED ELECTRODE AND METHOD OF PRODUCING DYE-SENSITIZED SOLAR CELL FUJIFILM CORPORATION (JP) 2015-10-01 US disclosed
US-20150062238-A1 BLACK INK COMPOSITION, INK SET, AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2015-03-05 US disclosed
US-20140371225-A1 PYRIDAZINONE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS FLATLEY DISCOVERY LAB (US) 2014-12-18 US disclosed
US-8545000-B2 Ink composition, ink set and image formation method FUJIFILM CORPORATION (JP) 2013-10-01 US disclosed
US-8529044-B2 Ink composition, ink set, and method of forming image FUJIFILM CORPORATION (JP) 2013-09-10 US disclosed
US-7842830-B2 Transition-metal charge-transport materials, methods of fabrication thereof, and methods of use thereof GEORGIA TECH RESEARCH CORPORATION (US) 2010-11-30 US disclosed
EP-2236567-A1 Dispersion containing water-insoluble colorant and production method thereof Fujifilm Corporation (JP) 2010-10-06 EP disclosed
US-20100249284-A1 DISPERSION CONTAINING WATER-INSOLUBLE COLORANT AND PRODUCTION METHOD THEREOF FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
US-20100189967-A1 WATER-INSOLUBLE COLORANT DISPERSION AND PRODUCTION METHOD THEREOF, AND RECORDING LIQUID, PRINTED ARTICLE, IMAGE-FORMING METHOD AND IMAGE-FORMING APPARATUS USING THE SAME FUJIFILM CORPORATION (JP) 2010-07-29 US disclosed
US-20100189967-A1 WATER-INSOLUBLE COLORANT DISPERSION AND PRODUCTION METHOD THEREOF, AND RECORDING LIQUID, PRINTED ARTICLE, IMAGE-FORMING METHOD AND IMAGE-FORMING APPARATUS USING THE SAME FUJIFILM CORPORATION (JP) 2010-07-29 US disclosed
US-20090065057-A1 Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof GEORGIA TECH RESEARCH CORPORATION 2009-03-12 US disclosed
US-20090065057-A1 Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof GEORGIA TECH RESEARCH CORPORATION 2009-03-12 US disclosed
US-20080121870-A1 Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof GEORGIA TECH RESEACH CORPORATION 2008-05-29 US disclosed
US-20080121870-A1 Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof GEORGIA TECH RESEACH CORPORATION 2008-05-29 US disclosed
EP-1707187-B1 Reductive colorant for keratin fibres WELLA AG (DE) 2007-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080121870-A1 Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof SLC39A3, SLC6A6, SLC6A9 MAPT 806/4885MAPK1 4317/4885KDM4E 3642/4885
US-20090065057-A1 Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof SLC9A3, SLC18A2, SLC9A2 MAPT 1876/4885MAPK1 4514/4885KDM4E 3683/4885
US-20140371225-A1 PYRIDAZINONE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS CFTR, NDUFB7, NDUFB5 MAPT 4864/4885MAPK1 1580/4885KDM4E 4123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.