SCHEMBL342431

SCHEMBL342431

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nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.32
PGD P52209 1/20 0.31
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3202743 1.00 TP53 (0.32) TP53PGDLMNAALOX15BLM
SCHEMBL28224690 1.00 TP53 (0.32) TP53PGDLMNAALOX15BLM
SCHEMBL7152817 1.00 TP53 (0.32) TP53PGDLMNAALOX15BLM
SCHEMBL30243032 1.00 TP53 (0.32) TP53PGDLMNAALOX15BLM
SCHEMBL3829374 1.00 TP53 (0.32) TP53PGDLMNAALOX15BLM
SCHEMBL5051622 1.00 TP53 (0.32) TP53PGDLMNAALOX15BLM
Hydrochloric Acid SCHEMBL15778876 0.97 TP53 (0.30) TP53PGD
SCHEMBL18902784 0.85 PGD (0.37) PGDLMNAALOX15BLMPMP22
SCHEMBL6686437 0.85 PGD (0.37) PGDLMNAALOX15BLMPMP22
SCHEMBL4449219 0.85 PGD (0.37) PGDLMNAALOX15BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116693814-A Block type sugar polymer and preparation method and application thereof 中国海洋大学 2023-09-05 CN claimed
CN-116693814-A Block type sugar polymer and preparation method and application thereof 中国海洋大学 2023-09-05 CN disclosed
CN-109553643-A The application of monosaccharide analog and molecular probe and the molecular probe comprising it 深圳先进技术研究院 2019-04-02 CN disclosed
US-9867884-B2 Vascular delivery systems BEN-GURION UNIVERSITY OF NEGEV RESEARCH & DEVELOPMENT AUTHORITY (IL) 2018-01-16 US disclosed
EP-2274017-B1 E-SELECTIN SPECIFIC VASCULAR DELIVERY SYSTEMS UNIV BEN GURION (IL) 2016-04-13 EP disclosed
US-20150056157-A1 VASCULAR DELIVERY SYSTEMS BEN-GURION UNIVERSITY OF NEGEV RESEARCH & DEVELOPMENT AUTHORITY (IL) 2015-02-26 US disclosed
US-8840874-B2 Vascular delivery systems BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2014-09-23 US disclosed
CN-103402525-A Methods of inhibiting protein fucosylation in vivo using fucose analogs SEATTLE GENETICS INC 2013-11-20 CN disclosed
US-20120014904-A1 VASCULAR DELIVERY SYSTEMS BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2012-01-19 US disclosed
EP-2274017-A2 VASCULAR DELIVERY SYSTEMS Ben Gurion University Of The Negev Research And Development Authority (IL) 2011-01-19 EP disclosed
WO-2009133545-A2 VASCULAR DELIVERY SYSTEMS BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2009-11-05 WO disclosed
US-5599915-A INHIBIT SELECTIN-MEDIATED CELLULAR ADHESION THE SCRIPPS RESEARCH INSTITUTE (US) 1997-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150056157-A1 VASCULAR DELIVERY SYSTEMS SELE, SELPLG, SELL TP53 1068/4885PGD 2399/4885LMNA 883/4885
US-20120014904-A1 VASCULAR DELIVERY SYSTEMS SELE, SELPLG, SELL TP53 1068/4885PGD 2399/4885LMNA 883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.