Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.52 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479764 | 1.00 | DGKA (0.55) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL197167 | 0.92 | DGKA (0.56) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL1933672 | 0.92 | DGKA (0.56) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL9935881 | 0.92 | DGKA (0.56) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL340251 | 0.92 | DGKA (0.56) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL3110064 | 0.92 | DGKA (0.56) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL9935331 | 0.92 | DGKA (0.56) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL341269 | 0.92 | DGKA (0.56) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL342390 | 0.92 | DGKA (0.56) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL2845569 | 0.91 | DGKA (0.53) | DGKAPRKCEPRKCQPRKCDPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283550-B1 | CATALYST CONTAINING AMIDINE GROUPS | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| EP-3294803-B1 | GUANIDINE GROUP CONTAINING CATALYST | SIKA TECH AG (CH) | 2020-12-09 | — | — | EP | disclosed |
| US-10414875-B2 | Catalyst containing guanidine groups | SIKA TECHNOLOGY AG (CH) | 2019-09-17 | — | — | US | disclosed |
| US-10392480-B2 | Catalyst containing amidine groups | SIKA TECHNOLOGY AG (CH) | 2019-08-27 | — | — | US | disclosed |
| US-20180171082-A1 | CATALYST CONTAINING AMIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2018-06-21 | — | — | US | disclosed |
| US-20180148545-A1 | CATALYST CONTAINING GUANIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2018-05-31 | — | — | US | disclosed |
| EP-3294803-A1 | CATALYST CONTAINING GUANIDINE GROUPS | Sika Technology AG (CH) | 2018-03-21 | — | — | EP | disclosed |
| EP-3283550-A1 | AMIDINE-GROUP CONTAINING CATALYST | Sika Technology AG (CH) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016180840-A1 | CATALYST CONTAINING GUANIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016166336-A1 | AMIDINE-GROUP CONTAINING CATALYST | SIKA TECHNOLOGY AG (CH) | 2016-10-20 | — | — | WO | disclosed |
| US-8759455-B2 | Two-stage curable composition containing a surface-deactivated polyisocyanate | SIKA TECHNOLOGY AG (CH) | 2014-06-24 | — | — | US | disclosed |
| US-20120045652-A1 | COMPOSITION CONTAINING A SURFACE-DEACTIVATED POLYISOCYANATE AND CURING IN TWO STAGES | SIKA TECHNOLOGY AG (CH) | 2012-02-23 | — | — | US | disclosed |
| EP-2414421-A1 | MOISTURE-REACTIVE POLYURETHANE COMPOSITION WITH ACCELERATED CURING ACHIEVED BY THE ACTION OF HEAT | Sika Technology AG (CH) | 2012-02-08 | — | — | EP | disclosed |
| US-20120012251-A1 | HOT CURING OR HEAT-ACTIVATED COMPOSITION CONTAINING A SURFACE-DEACTIVATED POLYISOCYANATE | SIKA TECHNOLOGY AG (CH) | 2012-01-19 | — | — | US | disclosed |
| EP-2236533-B1 | Heat curing or heat activatable composition comprising a surface deactivated polyisocyanate | SIKA TECHNOLOGY AG (CH) | 2011-11-09 | — | — | EP | disclosed |
| WO-2010112536-A1 | HOT CURING OR HEAT-ACTIVATED COMPOSITION CONTAINING A SURFACE-DEACTIVATED POLYISOCYANATE | SIKA TECHNOLOGY AG (CH) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010112535-A1 | MOISTURE-REACTIVE POLYURETHANE COMPOSITION WITH ACCELERATED CURING ACHIEVED BY THE ACTION OF HEAT | SIKA TECHNOLOGY AG (CH) | 2010-10-07 | — | — | WO | disclosed |
| EP-2236535-A1 | Humidity curing polyurethane composition being accelerated by influence of heat | Sika Technology AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| EP-2236533-A1 | Heat curing or heat activatable composition comprising a surface deactivated polyisocyanate | Sika Technology AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| EP-2236534-A1 | Composition curable in two stages comprising a surface deactivated polyisocyanate | Sika Technology AG (CH) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10414875-B2 | Catalyst containing guanidine groups | GMPS, GMNN, RNMT | DGKA 2753/4885PRKCE 3609/4885PRKCQ 3535/4885 |
| US-20180148545-A1 | CATALYST CONTAINING GUANIDINE GROUPS | GMPS, RNMT, GMNN | DGKA 2491/4885PRKCE 3418/4885PRKCQ 3305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.