Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3424872

N#[N+]c1ccccc1S(=O)(=O)O.[Cl-]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.39
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TTR P02766 2/20 0.37
FABP4 P15090 1/20 0.34
CCNA2 P20248 1/20 0.34
CDK2 P24941 1/20 0.34
MAPK14 Q16539 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
NR4A1 P22736 1/20 0.33
CYP1A2 P05177 2/20 0.33
COMT P21964 1/20 0.33
PGAM1 P18669 1/20 0.33
CHAT P28329 1/20 0.32
SNCA P37840 1/20 0.32
NAPRT Q6XQN6 1/20 0.31
POLB P06746 3/20 0.31
GAA P10253 2/20 0.31
NSD2 O96028 2/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8301266 0.98 MYC (0.40) MYCTSHRSMN1; SMN2TTRFABP4
Water SCHEMBL8022996 0.96 MYC (0.39) MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL28206790 0.90 MYC (0.36) MYCTSHRSMN1; SMN2TTRFABP4
Hydrochloric Acid SCHEMBL3422416 0.77 COMT (0.46) TTRCYP1A2COMTPOLBNSD2
SCHEMBL9094990 0.77 PKLR (0.34) PGAM1GAAMEN1KMT2ACA1
Hydrochloric Acid SCHEMBL3425440 0.75 TIMP3 (0.40) TSHRSMN1; SMN2TDP1SNCANAPRT
SCHEMBL2618027 0.75 TTR (0.46) TTRCYP1A2COMTNSD2ALDH1A1
Nitrogen SCHEMBL28287047 0.74 TSHR (0.50) MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL150335 0.74 TSHR (0.55) MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL29664068 0.74 TSHR (0.55) MYCTSHRSMN1; SMN2TTRFABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754273-B2 Method of printing a time-temperature indicator based on azo coupling reactions onto a susbtrate CIBA SPECIALTY CHEMICALS CORP. (US) 2010-07-13 US disclosed
US-20070218206-A1 Method of Printing a Time-Temperature Indicator Based on Azo Coupling Reactions onto a Susbtrate CIBA SPECIALTY CHEMICALS CORP. 2007-09-20 US disclosed
EP-1179034-B1 MIXTURES OF SYMMETRICAL AND UNSYMMETRICAL RED REACTIVE DYES EVERLIGHT USA INC (US) 2006-08-09 EP disclosed
EP-1179034-A4 MIXTURES OF SYMMETRICAL AND UNSYMMETRICAL RED REACTIVE DYES EVERLIGHT USA INC (US) 2004-10-06 EP disclosed
EP-1179034-A1 MIXTURES OF SYMMETRICAL AND UNSYMMETRICAL RED REACTIVE DYES Everlight USA, Inc. (US) 2002-02-13 EP disclosed
WO-2000068319-A1 MIXTURES OF SYMMETRICAL AND UNSYMMETRICAL RED REACTIVE DYES EVERLIGHT USA, INC. (US) 2000-11-16 WO disclosed
US-6068667-A Mixtures of symmetrical and unsymmetrical red reactive dyes EVERLIGHT USA, INC. (US) 2000-05-30 US disclosed
EP-0294762-A1 Process for producing 7-amino-6-demethyl-6-deoxytetracycline KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1988-12-14 EP disclosed