Maslinic Acid

Maslinic Acid

SCHEMBL3425459

CC1(C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@]43C)[C@H]2C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 8/20 1.00
PTPN2 P17706 4/20 1.00
AKR1B10 O60218 3/20 1.00
GPBAR1 Q8TDU6 3/20 1.00
PYGM P11217 1/20 1.00
AKR1B1 P15121 1/20 1.00
ALOX5 P09917 2/20 0.83
EGLN2 Q96KS0 1/20 0.80
EGLN1 Q9GZT9 1/20 0.80
EGLN3 Q9H6Z9 1/20 0.80
P4HTM Q9NXG6 1/20 0.80
POLB P06746 3/20 0.78
PSMB11 A5LHX3 2/20 0.78
PSMA7 O14818 2/20 0.78
PLA2G1B P04054 2/20 0.78
PTPRC P08575 2/20 0.78
PTPRF P10586 2/20 0.78
F3 P13726 2/20 0.78
PSMB1 P20618 2/20 0.78
CES1 P23141 2/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maslinic Acid SCHEMBL5797458 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Augustic Acid SCHEMBL829270 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL570425 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL24627035 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL13487363 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL23716504 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL19429613 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL22026389 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL21296155 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL14132395 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11944849-B2 Systems and methods for combined cosmetic treatment of cellulite with ultrasound ULTHERA, INC. (US) 2024-04-02 US disclosed
EP-3532008-B1 THE COSMETIC TREATMENT OF CELLULITE MERZ PHARMA GMBH & CO KGAA (DE) 2021-08-11 EP disclosed
US-20210093898-A1 SYSTEMS AND METHODS FOR COMBINED COSMETIC TREATMENT OF CELLULITE WITH ULTRASOUND ULTHERA INC. 2021-04-01 US disclosed
EP-3124047-A1 PENTACYCLIC TRITERPENOIDS FOR INJECTION LIPOLYSIS Merz Pharma GmbH & Co. KGaA (DE) 2017-02-01 EP disclosed
US-8822536-B2 Dietary supplements containing terpenoid acids of maslinic acid or oleanolic acid and process for enhancing muscle mass in mammals FHG CORPORATION (US) 2014-09-02 US disclosed
US-20130046018-A1 DIETARY SUPPLEMENTS CONTAINING TERPENOID ACIDS OF MASLINIC ACID OR OLEANOLIC ACID AND PROCESS FOR ENHANCING MUSCLE MASS IN MAMMALS FHG CORPORATION D/B/A INTEGRITY NUTRACEUTICALS (US) 2013-02-21 US disclosed
EP-2258374-A2 USE OF MASLINIC ACID FOR THE TREATMENT OF DISEASES AND THE SYMPTOMS THEREOF BY MEANS OF COX-2 INHIBITION Biomaslinic S.L. (ES) 2010-12-08 EP disclosed
US-20100204121-A1 DIETARY SUPPLEMENTS CONTAINING TERPENOID ACIDS OF MASLINIC ACID OR OLEANOLIC ACID AND PROCESS FOR ENHANCING MUSCLE MASS IN MAMMALS IN INGREDIENTS, INC. 2010-08-12 US disclosed
US-20090324801-A1 USE OF OLIVE EXTRACT AS A PRONUTRIENT IN ANIMAL FEED Hospital Real, Cuesta del Hospicio s/n (ES) 2009-12-31 US disclosed
US-20090179175-A1 METHOD FOR THE INDUSTRIAL USE OF TYROSOL AND HYDROXYTYROSOL CONTAINED IN THE SOLID BY- PRODUCTS OF INDUSTRIAL OLIVE CRUSHING UNIVERSIDAD DE GRANADA (ES) 2009-07-16 US disclosed
EP-1994835-A1 USE OF OLIVE EXTRACT AS A PRONUTRIENT IN ANIMAL FEED Universidad de Granada (ES) 2008-11-26 EP disclosed
EP-1987868-A1 METHOD FOR THE INDUSTRIAL USE OF TYROSOL AND HYDROXYTYROSOL CONTAINED IN THE SOLID BY-PRODUCTS OF INDUSTRIAL OLIVE CRUSHING Universidad de Granada (ES) 2008-11-05 EP disclosed
US-20060235078-A1 Insulin secretion potentiator USE-TECHNO CORPORATION 2006-10-19 US disclosed
EP-1674089-A1 ACCELERATOR FOR INITIAL INSULIN SECRETION Use-Techno Corporation (JP) 2006-06-28 EP disclosed
WO-2006064583-A1 TERPENE, METHOD FOR DETERMINING ITS BLOOD CONCENTRATION, AND METHOD FOR ANALYZING ITS PHARMACOKINETICS USE-TECHNO CORPORATION (JP) 2006-06-22 WO disclosed
WO-2006054370-A1 GLUCONEOGENESIS INHIBITING AGENT USE-TECHNO CORPORATION (JP) 2006-05-26 WO disclosed
US-20050143464-A1 With low side effects, which rapidly stimulate early insulin secretion and suppress blood glucose increase only at mealtimes; antidiabetic agent; triterpene acids or alcohols with picene ring; corosolic acids; oleanene acids; ursenoic acids; banaba plant extracts USE-TECHNO CORPORATION 2005-06-30 US disclosed
US-5916919-A TRITERPENES DALHOUSIE UNIVERSITY (CA) 1999-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050143464-A1 With low side effects, which rapidly stimulate early insulin secretion and suppress blood glucose increase only at mealtimes; antidiabetic agent; triterpene acids or alcohols with picene ring; corosolic acids; oleanene acids; ursenoic acids; banaba plant extracts GPR119, IRS1, AMY1A PTPN1 1873/4885PTPN2 2179/4885AKR1B10 1998/4885
US-20210093898-A1 SYSTEMS AND METHODS FOR COMBINED COSMETIC TREATMENT OF CELLULITE WITH ULTRASOUND CUTA, DSTN, MMP1 PTPN1 3261/4885PTPN2 3287/4885AKR1B10 2852/4885
US-20060235078-A1 Insulin secretion potentiator IAPP, GPR119, IRS1 PTPN1 1481/4885PTPN2 1100/4885AKR1B10 1544/4885
US-11944849-B2 Systems and methods for combined cosmetic treatment of cellulite with ultrasound CUTA, DSTN, MMP1 PTPN1 3261/4885PTPN2 3287/4885AKR1B10 2852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.