Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31504610 | 0.89 | L3MBTL1 (0.54) | LMNAL3MBTL1BRD4BRD2CHEK1 | |
| SCHEMBL26167674 | 0.84 | LMNA (0.70) | LMNAL3MBTL1BRD4BRD2CHEK1 | |
| SCHEMBL9044830 | 0.78 | MAPT (0.53) | LMNAL3MBTL1TP53MAPTPTGS2 | |
| SCHEMBL11313288 | 0.78 | ALDH1A1 (0.50) | LMNAL3MBTL1BRD4BRD2FABP3 | |
| SCHEMBL12936275 | 0.78 | LMNA (0.41) | LMNAL3MBTL1BRD4BRD2CHEK1 | |
| SCHEMBL16461405 | 0.73 | LMNA (0.47) | LMNAL3MBTL1BRD4BRD2CHEK1 | |
| SCHEMBL27479263 | 0.73 | L3MBTL1 (0.39) | LMNAL3MBTL1FABP3FABP4TP53 | |
| SCHEMBL13385360 | 0.73 | LMNA (0.47) | LMNABRD4BRD2FABP3FABP4 | |
| SCHEMBL2872108 | 0.72 | MAOB (0.51) | LMNAL3MBTL1BRD4BRD2CHEK1 | |
| SCHEMBL3427195 | 0.71 | MEN1 (0.65) | LMNAL3MBTL1MAPTHTTADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7731985-B2 | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |
| EP-1484971-B1 | USE OF 4-AMINOPYRIMIDINES FOR THE ANTIMICROBIAL TREATMENT OF SURFACES | CIBA SC HOLDING AG (CH) | 2007-07-04 | — | — | EP | disclosed |
| US-20050143387-A1 | 4-Aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORP. | 2005-06-30 | — | — | US | disclosed |
| EP-1484971-A1 | 4-AMINOPYRIMIDINES AND THEIR USE FOR THE ANTIMICROBIAL TREATMENT OF SURFACES | Ciba SC Holding AG (CH) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003077656-A1 | 4-AMINOPYRIMIDINES AND THEIR USE FOR THE ANTIMICROBIAL TREATMENT OF SURFACES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143387-A1 | 4-Aminopyrimidines and their use for the antimicrobial treatment of surfaces | DPM1, UNG, DPYD | LMNA 4211/4885L3MBTL1 2796/4885BRD4 3326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.