Trolamine

Trolamine

SCHEMBL342588

CCl.OCCN(CCO)CCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
HPGD P15428 2/20 0.44
MAPK1 P28482 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HTT P42858 1/20 0.37
ALOX15 P16050 1/20 0.36
LMNA P02545 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
TSHR P16473 2/20 0.32
BCHE P06276 1/20 0.31
ALDH2 P05091 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL721955 0.88 MAPT (0.50) MAPTHPGDMAPK1CYP1A2CYP2C9
Trolamine SCHEMBL28156459 0.88 MAPT (0.50) MAPTHPGDMAPK1CYP1A2CYP2C9
Trolamine SCHEMBL17938713 0.88 MAPT (0.43) MAPTHPGDMAPK1CYP1A2CYP2C9
Trolamine SCHEMBL1146 0.88 MAPT (0.47) MAPTHPGDMAPK1CYP1A2CYP2C9
Trolamine SCHEMBL4748243 0.88 MAPT (0.47) MAPTHPGDMAPK1CYP1A2CYP2C9
Trolamine SCHEMBL15845959 0.88 MAPT (0.47) MAPTHPGDMAPK1CYP1A2CYP2C9
Trolamine SCHEMBL434089 0.88 MAPT (0.47) MAPTHPGDMAPK1CYP1A2CYP2C9
Trolamine SCHEMBL8616286 0.86 MAPT (0.42) MAPTHPGDMAPK1CYP1A2CYP2C9
Trolamine SCHEMBL11800024 0.85 MAPT (0.47) MAPTHPGDMAPK1CYP1A2CYP2C9
Trolamine SCHEMBL752321 0.85 MAPT (0.47) MAPTHPGDMAPK1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3820968-A1 METHODS OF USING IONIC LIQUIDS AS DEMULSIFIERS BAKER HUGHES HOLDINGS LLC (US) 2021-05-19 EP claimed
US-5908814-A REACTION PRODUCT OF TERTIARY AMINE AND ALKYL HALIDE M-I L.L.C. (US) 1999-06-01 US claimed
EP-0634468-B1 Drilling fluid additive and method for reducing the swelling of clay MI LLC (US) 1998-11-11 EP claimed
EP-0634468-A1 Drilling fluid additive and method for inhibiting hydration M-I DRILLING FLUIDS COMPANY (US) 1995-01-18 EP claimed
US-5350740-A Controlling swelling of clays with quaternary ammonium compounds M-1 DRILLING FLUIDS COMPANY (US) 1994-09-27 US claimed
US-12031089-B2 Ceramic foundry media and related methods CARBO CERAMICS INC. (US) 2024-07-09 US disclosed
CN-114651053-B Coated composites comprising delayed release agents and methods of use thereof 贝克休斯油田作业有限责任公司 2024-05-24 CN disclosed
US-20230399562-A1 INFUSED AND COATED PROPPANT CONTAINING CHEMICAL TREATMENT AGENTS AND METHODS OF USING SAME CARBO CERAMICS INC. 2023-12-14 US disclosed
US-11739260-B2 Infused and coated proppant containing chemical treatment agents and methods of using same CARBO CERAMICS INC. (US) 2023-08-29 US disclosed
US-11624023-B2 Catalyst particles and methods for making same CARBO CERAMICS INC. (US) 2023-04-11 US disclosed
EP-3289041-B1 METHODS USING A SUSTAINED RELEASE SYSTEM FOR RESERVOIR TREATMENT AND MONITORING JOHNSON MATTHEY PLC (GB) 2023-03-08 EP disclosed
CN-114651053-A Coated composite comprising delayed release agent and method of use thereof 贝克休斯油田作业有限责任公司 2022-06-21 CN disclosed
US-7833947-B1 Method for treatment of a well using high solid content fluid delivery SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2010-11-16 US disclosed
US-7493955-B2 Well treating compositions for slow release of treatment agents and methods of using the same BJ SERVICES COMPANY (US) 2009-02-24 US disclosed
US-20060124302-A1 Well treating compositions for slow release of treatment agents and methods of using the same BJ SERVICES COMPANY 2006-06-15 US disclosed
US-20040110877-A1 ethylene vinyl acetate copolymer, a surface active agent other than an ethylene vinyl acetate copolymer and a bipolar solvent has a boiling point higher than the melting point of the ethylene vinyl acetate copolymer BAKER HUGHES, A GE COMPANY, LLC 2004-06-10 US disclosed
EP-0634468-B1 Drilling fluid additive and method for reducing the swelling of clay MI LLC (US) 1998-11-11 EP disclosed
EP-0838514-A1 Drilling fluid additive and method for inhibiting hydration M-I Drilling Fluids L.L.C. (US) 1998-04-29 EP disclosed
EP-0634468-A1 Drilling fluid additive and method for inhibiting hydration M-I DRILLING FLUIDS COMPANY (US) 1995-01-18 EP disclosed
US-5350740-A Controlling swelling of clays with quaternary ammonium compounds M-1 DRILLING FLUIDS COMPANY (US) 1994-09-27 US disclosed