Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trolamine SCHEMBL28067402 | 0.93 | LMNA (0.41) | MAPTHPGDMAPK1CYP1A2CYP2C9 | |
| Trolamine SCHEMBL721955 | 0.89 | MAPT (0.50) | MAPTHPGDMAPK1CYP1A2CYP2C9 | |
| Trolamine SCHEMBL342588 | 0.86 | MAPT (0.47) | MAPTHPGDMAPK1CYP1A2CYP2C9 | |
| Trolamine SCHEMBL27619468 | 0.86 | MAPT (0.47) | MAPTHPGDMAPK1CYP1A2CYP2C9 | |
| Trolamine SCHEMBL28156459 | 0.82 | MAPT (0.50) | MAPTHPGDMAPK1CYP1A2CYP2C9 | |
| Trolamine SCHEMBL17938713 | 0.82 | MAPT (0.43) | MAPTHPGDMAPK1CYP1A2CYP2C9 | |
| Trolamine SCHEMBL15845959 | 0.82 | MAPT (0.47) | MAPTHPGDMAPK1CYP1A2CYP2C9 | |
| Trolamine SCHEMBL1146 | 0.82 | MAPT (0.47) | MAPTHPGDMAPK1CYP1A2CYP2C9 | |
| Trolamine SCHEMBL434089 | 0.82 | MAPT (0.47) | MAPTHPGDMAPK1CYP1A2CYP2C9 | |
| Trolamine SCHEMBL4748243 | 0.82 | MAPT (0.47) | MAPTHPGDMAPK1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750550-A | RESPIRATORY SYSTEM DISORDERS | SANOFI (FR) | 1998-05-12 | — | — | US | disclosed |