Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3682793 | 1.00 | TSHR (0.36) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL11146222 | 0.71 | NPC1 (0.37) | TSHRIDO1AGXTALDH1A1CYP2C19 | |
| SCHEMBL3185636 | 0.70 | MAOB (0.32) | IDO1 | |
| SCHEMBL22125222 | 0.69 | MAOA (0.33) | IDO1CA1CA2CA9SLC6A3 | |
| SCHEMBL485261 | 0.69 | TSHR (0.35) | TSHRIDO1AGXTCYP2C19 | |
| SCHEMBL7868292 | 0.69 | TSHR (0.35) | TSHRIDO1AGXTCYP2C19 | |
| SCHEMBL11279266 | 0.67 | ALDH1A1 (0.40) | TSHRALDH1A1CYP2C19 | |
| SCHEMBL28018292 | 0.67 | TSHR (0.36) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL2856970 | 0.65 | TSHR (0.52) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL27509183 | 0.65 | TSHR (0.57) | TSHRIDO1AGXTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411354-B2 | STABILIZATION OF POLYOLS | LANXESS DEUTSCHLAND GMBH (DE) | 2017-10-04 | — | — | EP | disclosed |
| US-9464164-B2 | Method for the preparation of polyesters | LANXESS DEUTSCHLAND GMBH (DE) | 2016-10-11 | — | — | US | disclosed |
| US-9464164-B2 | Method for the preparation of polyesters | LANXESS DEUTSCHLAND GMBH (DE) | 2016-10-11 | — | — | US | disclosed |
| US-20120101252-A1 | STABILIZATION OF POLYOLS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
| US-20120101252-A1 | STABILIZATION OF POLYOLS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
| WO-2010108840-A1 | STABILIZATION OF POLYOLS | LANXESS DEUTSCHLAND GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101252-A1 | STABILIZATION OF POLYOLS | PUF60, PCBP1, PHOSPHO1 | TSHR 4670/4885IDO1 4058/4885AGXT 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.