Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426423 | 1.00 | TSHR (0.36) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL11146222 | 0.71 | NPC1 (0.37) | TSHRIDO1AGXTALDH1A1CYP2C19 | |
| SCHEMBL3185636 | 0.70 | MAOB (0.32) | IDO1 | |
| SCHEMBL22125222 | 0.69 | MAOA (0.33) | IDO1CA1CA2CA9SLC6A3 | |
| SCHEMBL485261 | 0.69 | TSHR (0.35) | TSHRIDO1AGXTCYP2C19 | |
| SCHEMBL7868292 | 0.69 | TSHR (0.35) | TSHRIDO1AGXTCYP2C19 | |
| SCHEMBL11279266 | 0.67 | ALDH1A1 (0.40) | TSHRALDH1A1CYP2C19 | |
| SCHEMBL28018292 | 0.67 | TSHR (0.36) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL2856970 | 0.65 | TSHR (0.52) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL27509183 | 0.65 | TSHR (0.57) | TSHRIDO1AGXTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731118-B1 | Low viscosity polymer polyols, a process for their preparation and their use in the preparation of polyurethane foam | BAYER AG (DE) | 2001-10-17 | — | — | EP | claimed |
| EP-0768324-B1 | Continuous process for the preparation of highly stable, finely divided, low viscosity polymer polyols of small average particle size | BAYER AG (DE) | 2000-08-16 | — | — | EP | claimed |
| US-5814699-A | CATALYTIC CONDENSATION COPOLYMERIZATION OF ACRYLONITRILE AND STYRENE WITH BASIC POLYOLS AND MACRONOMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-29 | — | — | US | claimed |
| EP-0768324-A1 | Continuous process for the preparation of highly stable, finely divided, low viscosity polymer polyols of small average particle size | BAYER AG (DE) | 1997-04-16 | — | — | EP | claimed |
| EP-0731118-A2 | Low viscosity polymer polyols, a process for their preparation and their use in the preparation of polyurethane foam | BAYER AG (DE) | 1996-09-11 | — | — | EP | claimed |
| US-5554662-A | POLYMERIZATION IN PRESENCE OF BASE POLYOL, MACROMER, AND ENOL ETHER | BAYER ADTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | claimed |
| WO-2023189908-A1 | RUBBER COMPOSITION, VULCANIZATE, AND VULCANIZED MOLDED OBJECT | デンカ株式会社 | 2023-10-05 | — | — | WO | disclosed |
| EP-3921353-B1 | NOVEL POLYMER POLYOL STABILIZERS | COVESTRO LLC (US) | 2023-03-15 | — | — | EP | disclosed |
| US-11421063-B2 | Preformed stabilizers with improved stability | COVESTRO LLC (US) | 2022-08-23 | — | — | US | disclosed |
| EP-4041787-A1 | PREFORMED STABILIZERS WITH IMPROVED STABILITY | Covestro LLC (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114599698-A | Preformed stabilizers with improved stability | 科思创有限公司 | 2022-06-07 | — | — | CN | disclosed |
| EP-3921353-A1 | NOVEL POLYMER POLYOL STABILIZERS | Covestro LLC (US) | 2021-12-15 | — | — | EP | disclosed |
| CN-113383027-A | Novel polymer polyol stabilizers | 科思创有限公司 | 2021-09-10 | — | — | CN | disclosed |
| EP-0768324-A1 | Continuous process for the preparation of highly stable, finely divided, low viscosity polymer polyols of small average particle size | BAYER AG (DE) | 1997-04-16 | — | — | EP | disclosed |
| EP-0755953-A2 | Low viscosity polymer polyols, process for their preparation and their use in the preparation of polyurethane foams | BAYER AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| US-5594066-A | Low-viscosity, stable, agglomerate-free polymer polyols, a process for their preparation and their use in producing polyurethane plastics | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| EP-0731118-A2 | Low viscosity polymer polyols, a process for their preparation and their use in the preparation of polyurethane foam | BAYER AG (DE) | 1996-09-11 | — | — | EP | disclosed |
| US-5554662-A | POLYMERIZATION IN PRESENCE OF BASE POLYOL, MACROMER, AND ENOL ETHER | BAYER ADTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |
| EP-0699693-A2 | Low viscosity, stable, non-agglomerated polymer-polyols, their preparation and use in the preparation of polyurethanes | BAYER AG (DE) | 1996-03-06 | — | — | EP | disclosed |
| EP-0636647-A1 | Use of substituted phenols as fatique protectors for dynamically stressed elastomers | BAYER AG (DE) | 1995-02-01 | — | — | EP | disclosed |