Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP1CA | P62136 | 4/20 | 0.48 |
| ▸ | MARS1 | P56192 | 1/20 | 0.47 |
| ▸ | RPA1 | P27694 | 11/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431022 | 0.90 | RPA1 (0.47) | PPP1CAMARS1RPA1MEN1KMT2A | |
| SCHEMBL14995317 | 0.89 | MARS1 (0.41) | PPP1CAMARS1RPA1MEN1KMT2A | |
| SCHEMBL14995472 | 0.89 | PTGS2 (0.43) | PPP1CAMARS1RPA1MEN1KMT2A | |
| SCHEMBL3430216 | 0.88 | RPA1 (0.47) | PPP1CAMARS1RPA1MEN1KMT2A | |
| SCHEMBL14995459 | 0.88 | RPA1 (0.41) | PPP1CAMARS1RPA1MEN1KMT2A | |
| SCHEMBL3429253 | 0.87 | RPA1 (0.42) | PPP1CAMARS1RPA1MEN1KMT2A | |
| SCHEMBL14995442 | 0.87 | RPA1 (0.40) | PPP1CAMARS1RPA1MEN1KMT2A | |
| SCHEMBL3427714 | 0.87 | RPA1 (0.43) | PPP1CAMARS1RPA1MEN1KMT2A | |
| SCHEMBL3430065 | 0.86 | RPA1 (0.44) | RPA1KMT2APOLB | |
| SCHEMBL3434938 | 0.85 | RPA1 (0.45) | PPP1CAMARS1RPA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361309-B1 | METHOD | OXFORD BIOMEDICA LTD (GB) | 2016-07-27 | — | — | EP | disclosed |
| US-20120295960-A1 | TREATMENT REGIMEN FOR PARKINSON'S DISEASE | OXFORD BIOMEDICA (UK) LTD. | 2012-11-22 | — | — | US | disclosed |
| WO-2010055290-A1 | METHOD | OXFORD BIOMEDICA (UK) LIMITED (GB) | 2010-05-20 | — | — | WO | disclosed |
| WO-2008048057-A1 | MYONECTIN AND USES THEREOF | MITOCON LTD. (KR) | 2008-04-24 | — | — | WO | disclosed |