Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | MARS1 | P56192 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3427714 | 0.89 | RPA1 (0.43) | RPA1MEN1KMT2AATMRXRA | |
| SCHEMBL3427568 | 0.87 | RPA1 (0.46) | RPA1MEN1KMT2AATMRXRA | |
| SCHEMBL3427858 | 0.87 | PPP1CA (0.48) | RPA1MEN1KMT2AATMPPP1CA | |
| SCHEMBL3431022 | 0.86 | RPA1 (0.47) | RPA1MEN1KMT2AATMPPP1CA | |
| SCHEMBL3434938 | 0.86 | RPA1 (0.45) | RPA1MEN1KMT2AATMRXRA | |
| SCHEMBL14995442 | 0.85 | RPA1 (0.40) | RPA1MEN1KMT2AATMRXRA | |
| SCHEMBL1765503 | 0.84 | RPA1 (0.61) | RPA1MEN1KMT2AATMPPP1CA | |
| SCHEMBL14995459 | 0.82 | RPA1 (0.41) | RPA1MEN1KMT2AATMRXRA | |
| SCHEMBL3428855 | 0.81 | PPP1CA (0.50) | MEN1KMT2AATMRXRARXRB | |
| SCHEMBL14995472 | 0.81 | PTGS2 (0.43) | RPA1MEN1KMT2AATMPPP1CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254885-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |