Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 8/20 | 0.54 |
| ▸ | SLC16A1 | P53985 | 8/20 | 0.54 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.48 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | CCKAR | P32238 | 3/20 | 0.42 |
| ▸ | RPA1 | P27694 | 3/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.40 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | MARS1 | P56192 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428855 | 0.90 | PPP1CA (0.50) | SLC16A3SLC16A1MCTS1PPP1CARXRA | |
| SCHEMBL3427568 | 0.89 | RPA1 (0.46) | SLC16A3SLC16A1MCTS1RXRARXRB | |
| SCHEMBL3429676 | 0.89 | PPP1CA (0.46) | SLC16A3SLC16A1MCTS1PPP1CARXRA | |
| SCHEMBL3432282 | 0.88 | RXRA (0.52) | SLC16A3SLC16A1MCTS1PPP1CARXRA | |
| SCHEMBL3428152 | 0.88 | SLC16A3 (0.50) | SLC16A3SLC16A1MCTS1PPP1CARXRA | |
| SCHEMBL3430532 | 0.87 | SLC16A3 (0.62) | SLC16A3SLC16A1MCTS1PPP1CACCKAR | |
| SCHEMBL1765022 | 0.85 | PPP1CA (0.63) | SLC16A3SLC16A1MCTS1PPP1CACCKAR | |
| SCHEMBL3428061 | 0.83 | SLC16A3 (0.48) | SLC16A3SLC16A1MCTS1RPA1NSD2 | |
| SCHEMBL3434215 | 0.83 | PGR (0.44) | SLC16A3SLC16A1MCTS1PPP1CARXRA | |
| SCHEMBL1110857 | 0.81 | PPP1CA (0.57) | SLC16A3SLC16A1MCTS1PPP1CARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254885-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |