Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 7/20 | 0.50 |
| ▸ | SLC16A1 | P53985 | 7/20 | 0.50 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CCKAR | P32238 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431941 | 0.92 | ALDH1A1 (0.45) | SLC16A3SLC16A1MCTS1ALDH1A1RXRA | |
| SCHEMBL3428695 | 0.91 | ALDH1A1 (0.44) | SLC16A3SLC16A1MCTS1ALDH1A1RXRA | |
| SCHEMBL3431428 | 0.91 | RXRA (0.47) | SLC16A3SLC16A1MCTS1ALDH1A1RXRA | |
| SCHEMBL3429460 | 0.90 | RPA1 (0.41) | SLC16A3SLC16A1ALDH1A1RXRARXRB | |
| SCHEMBL3426584 | 0.89 | SLC16A3 (0.57) | SLC16A3SLC16A1MCTS1ALDH1A1CCKAR | |
| SCHEMBL3428023 | 0.88 | SLC16A3 (0.54) | SLC16A3SLC16A1MCTS1CCKARRXRA | |
| SCHEMBL3433370 | 0.85 | ALDH1A1 (0.41) | SLC16A3SLC16A1MCTS1ALDH1A1RXRA | |
| SCHEMBL1765360 | 0.85 | SLC16A3 (0.52) | SLC16A3SLC16A1MCTS1ALDH1A1CCKAR | |
| SCHEMBL3429299 | 0.85 | ALDH1A1 (0.46) | SLC16A3SLC16A1MCTS1ALDH1A1LMNA | |
| SCHEMBL3427632 | 0.84 | ALDH1A1 (0.44) | SLC16A3SLC16A1MCTS1ALDH1A1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254885-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |