Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP1CA | P62136 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 4/20 | 0.48 |
| ▸ | RXRB | P28702 | 4/20 | 0.48 |
| ▸ | RXRG | P48443 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MARS1 | P56192 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3432282 | 0.95 | RXRA (0.52) | PPP1CARXRARXRBRXRGKMT2A | |
| SCHEMBL3429676 | 0.93 | PPP1CA (0.46) | PPP1CARXRARXRBRXRGKMT2A | |
| SCHEMBL3428023 | 0.90 | SLC16A3 (0.54) | PPP1CARXRARXRBRXRGSLC16A3 | |
| SCHEMBL3434215 | 0.90 | PGR (0.44) | PPP1CARXRARXRBRXRGKMT2A | |
| SCHEMBL1110857 | 0.88 | PPP1CA (0.57) | PPP1CARXRARXRBRXRGKMT2A | |
| SCHEMBL3427676 | 0.87 | PPP1CA (0.52) | PPP1CARXRARXRBRXRGKMT2A | |
| SCHEMBL6053761 | 0.86 | PPP1CA (0.67) | PPP1CARXRARXRBRXRGKMT2A | |
| SCHEMBL3429834 | 0.85 | RXRA (0.50) | PPP1CARXRARXRBRXRGKMT2A | |
| SCHEMBL3431908 | 0.85 | KMT2A (0.51) | PPP1CARXRARXRBRXRGKMT2A | |
| SCHEMBL3431941 | 0.85 | ALDH1A1 (0.45) | PPP1CARXRARXRBRXRGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254885-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |