SCHEMBL3428686

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16921567	0.87	HSD17B2 (0.38)	HSD17B2ALOX5EPHX2LIPGNPSR1
	SCHEMBL752989	0.83	SMN1; SMN2 (0.42)	HSD17B2ALOX5EPHX2LIPGNPSR1
	SCHEMBL752004	0.81	ALDH1A1 (0.40)	LIPGNPSR1CCR6MEN1KMT2A
	SCHEMBL754318	0.79	LIPG (0.36)	LIPGNPSR1CCR6MEN1KMT2A
	SCHEMBL2779143	0.78	NPSR1 (0.39)	LIPGNPSR1SMN1; SMN2CCR6GAA
	SCHEMBL753282	0.78	LIPG (0.37)	HSD17B2LIPGNPSR1CCR6TDP1
	SCHEMBL752847	0.78	LIPG (0.35)	HSD17B2LIPGNPSR1SMN1; SMN2CCR6
	SCHEMBL752712	0.78	LIPG (0.35)	LIPGNPSR1CCR6TDP1MEN1
	SCHEMBL752870	0.77	LIPG (0.35)	LIPGNPSR1MAPT
	SCHEMBL754559	0.77	LIPG (0.35)	LIPGALDH1A1KDM4EHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.