Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.44 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.44 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.44 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CCKAR | P32238 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425186 | 0.93 | CHRNA7 (0.45) | FAAHMGLLCHRNA7DYRK3DYRK1A | |
| SCHEMBL3431896 | 0.91 | FAAH (0.47) | FAAHMGLLCHRNA7SLC16A3SLC16A1 | |
| SCHEMBL3431433 | 0.88 | RXRA (0.47) | FAAHMGLLCHRNA7SLC16A3SLC16A1 | |
| SCHEMBL1110698 | 0.88 | PPP1CA (0.50) | FAAHCHRNA7SLC16A3SLC16A1MCTS1 | |
| SCHEMBL3430227 | 0.87 | ALDH1A1 (0.45) | FAAHMGLLCHRNA7DYRK3DYRK1A | |
| SCHEMBL3434465 | 0.86 | ALDH1A1 (0.44) | CHRNA7DYRK3DYRK1ADYRK2DYRK1B | |
| SCHEMBL3426584 | 0.85 | SLC16A3 (0.57) | FAAHMGLLSLC16A3SLC16A1MCTS1 | |
| SCHEMBL3427612 | 0.85 | NPY5R (0.47) | FAAHDYRK3DYRK1ADYRK2DYRK1B | |
| SCHEMBL3434918 | 0.85 | ALDH1A1 (0.40) | FAAHMGLLCHRNA7DYRK3DYRK1A | |
| SCHEMBL1110649 | 0.85 | ALDH1A1 (0.44) | FAAHCHRNA7DYRK3DYRK1ADYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254885-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |