Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 7/20 | 0.44 |
| ▸ | SLC16A1 | P53985 | 7/20 | 0.44 |
| ▸ | MCTS1 | Q9ULC4 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426584 | 0.88 | SLC16A3 (0.57) | ALDH1A1NPSR1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL3431434 | 0.88 | CHRNA7 (0.47) | ALDH1A1NPSR1FAAHTHRBCA9 | |
| SCHEMBL1110815 | 0.87 | SLC5A1 (0.47) | ALDH1A1NPSR1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL3428061 | 0.86 | SLC16A3 (0.48) | SLC16A3SLC16A1MCTS1MAPTPOLB | |
| SCHEMBL3431896 | 0.85 | FAAH (0.47) | SLC16A3SLC16A1MCTS1FAAHTHRB | |
| SCHEMBL3428152 | 0.85 | SLC16A3 (0.50) | ALDH1A1NPSR1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL3427610 | 0.84 | RPA1 (0.45) | ALDH1A1FAAHPOLBTHRBMGLL | |
| SCHEMBL1765356 | 0.84 | FAAH (0.56) | ALDH1A1NPSR1FAAHPOLBTHRB | |
| SCHEMBL3431941 | 0.82 | ALDH1A1 (0.45) | ALDH1A1NPSR1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL3431428 | 0.80 | RXRA (0.47) | ALDH1A1NPSR1SLC16A3SLC16A1MCTS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254885-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |