Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.53 |
| ▸ | ABAT | P80404 | 3/20 | 0.53 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954180 | 1.00 | PTGS2 (0.59) | PTGS2KDM4ERAB9AALDH1A1ALDH5A1 | |
| SCHEMBL3429484 | 0.86 | KDM4E (0.53) | PTGS2KDM4ERAB9AALDH1A1ALDH5A1 | |
| SCHEMBL1824019 | 0.85 | LCK (0.54) | PTGS2KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL1824017 | 0.85 | LCK (0.54) | PTGS2KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL7507833 | 0.85 | KDM4E (0.61) | PTGS2KDM4ERAB9AALDH1A1ALDH5A1 | |
| SCHEMBL29289429 | 0.85 | PRKCI (0.61) | PTGS2KDM4ERAB9AALDH1A1ALDH5A1 | |
| SCHEMBL3430982 | 0.83 | ALDH1A1 (0.50) | PTGS2KDM4ERAB9AALDH1A1ALDH5A1 | |
| SCHEMBL4371754 | 0.83 | KDM4E (0.59) | PTGS2KDM4ERAB9AALDH1A1ALDH5A1 | |
| SCHEMBL3431177 | 0.83 | KDM4E (0.59) | PTGS2KDM4ERAB9AALDH1A1ALDH5A1 | |
| SCHEMBL30225085 | 0.83 | KDM4E (0.59) | PTGS2KDM4ERAB9AALDH1A1ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1589136-A | Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups | CUTANIX CORP (US) | 2005-03-02 | — | — | CN | claimed |
| US-20030157154-A1 | Compositions containing hydroxy aromatic aldehydes and their use in treatments | CUTANIX CORPORATION | 2003-08-21 | — | — | US | claimed |
| US-5395978-A | Process for selective preparation of hydroxybenzaldehydes | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | claimed |
| US-12459883-B2 | Substituted hydroxystilbene compounds and derivatives synthesis and uses thereof | Kynan Duke IP, LLC (US) | 2025-11-04 | — | — | US | disclosed |
| WO-2025061824-A1 | COMPOSITIONS AND METHODS FOR REDUCING APPETITE AND/OR FACILITATING WEIGHT LOSS | JELLYNOV (FR) | 2025-03-27 | — | — | WO | disclosed |
| WO-2025061830-A1 | COMPOSITIONS AND METHODS FOR REDUCING APPETITE AND/OR FACILITATING WEIGHT LOSS | JELLYNOV (FR) | 2025-03-27 | — | — | WO | disclosed |
| US-12178906-B2 | Method of administering a self-foaming composition | JELLYNOV (FR) | 2024-12-31 | — | — | US | disclosed |
| US-20240026390-A1 | CULTURE COMPOSITIONS AND METHODS OF THEIR USE FOR HIGH YIELD PRODUCTION OF VANILLIN | EUAGORE, LLC | 2024-01-25 | — | — | US | disclosed |
| US-20230159421-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | Kynan Duke IP, LLC (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159421-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | Kynan Duke IP, LLC (US) | 2023-05-25 | — | — | US | disclosed |
| US-20220409529-A1 | METHOD OF ADMINISTERING A SELF-FOAMING COMPOSITION | JELLYNOV (FR) | 2022-12-29 | — | — | US | disclosed |
| EP-0599148-B1 | Process for the selective preparation of hydroxybenzaldehydes | HOECHST AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| US-5395978-A | Process for selective preparation of hydroxybenzaldehydes | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0599148-A1 | Process for the selective preparation of hydroxybenzaldehydes | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-01 | — | — | EP | disclosed |
| EP-0193853-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4783462-A | 3(2H)pyridazinone, and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-11-08 | — | — | US | disclosed |
| EP-0193853-A2 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-09-10 | — | — | EP | disclosed |
| US-4157286-A | Production of 1,2-bis(hydroxyphenyl)ethane-1,2-diols by electrolytic reduction | MONSANTO COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-4133729-A | Production of 1,2-bis(hydroxy-phenyl)ethane-1,2-diols by electrolytic reduction | MONSANTO COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4087336-A | Electrolytic reductive coupling of hydroxybenzaldehydes | MONSANTO COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030157154-A1 | Compositions containing hydroxy aromatic aldehydes and their use in treatments | TYR, HRH1, HRH2 | PTGS2 484/4885KDM4E 2158/4885RAB9A 4360/4885 |
| US-12178906-B2 | Method of administering a self-foaming composition | FABP6, PNLIP, MGLL | PTGS2 992/4885KDM4E 3508/4885RAB9A 3571/4885 |
| US-20220409529-A1 | METHOD OF ADMINISTERING A SELF-FOAMING COMPOSITION | FABP6, PNLIP, MGLL | PTGS2 992/4885KDM4E 3508/4885RAB9A 3571/4885 |
| US-12459883-B2 | Substituted hydroxystilbene compounds and derivatives synthesis and uses thereof | CYP8B1, HSD11B1, HSD11B2 | PTGS2 213/4885KDM4E 3324/4885RAB9A 3696/4885 |
| US-20230159421-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | CYP8B1, HSD11B1, HSD11B2 | PTGS2 213/4885KDM4E 3324/4885RAB9A 3696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.