SCHEMBL342980

SCHEMBL342980

CC(=O)CC(C)C(O)=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15652934 1.00
Hydrochloric Acid SCHEMBL10781424 0.97 ALDH1A1 (0.48)
SCHEMBL1579950 0.81
SCHEMBL3833284 0.78
SCHEMBL599696 0.78
SCHEMBL10175142 0.78
SCHEMBL6946313 0.77
SCHEMBL9068959 0.77
SCHEMBL9749195 0.77
SCHEMBL9416705 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4411836-A HEATING IN PRESENCE OF FATTY OR AROMATIC ACID SALT OR TERTIARY AMINE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-25 US claimed
JP-9295963-A None JP disclosed
CN-118956813-A Modified esterases and their use 天野酶制品株式会社 2024-11-15 CN disclosed
CN-112055751-B Modified esterases and their use 天野酶制品株式会社 2024-09-24 CN disclosed
EP-2450194-B1 Recording medium CANON KK (JP) 2015-06-17 EP disclosed
US-8722159-B2 Recording medium CANON KABUSHIKI KAISHA (JP) 2014-05-13 US disclosed
EP-2450194-A2 Recording medium Canon Kabushiki Kaisha (JP) 2012-05-09 EP disclosed
US-20120015119-A1 RECORDING MEDIUM CANON KABUSHIKI KAISHA (JP) 2012-01-19 US disclosed
US-20080161597-A1 Method For the Production of a Thioacetic Acid and Salts Thereof LONZA AG (CH) 2008-07-03 US disclosed
US-6596898-B2 Making a 2-fluoro-2-chlorocyclopropanecarboxylic acid derivative stereoselectively in high yield by reacting a diazoacetic acid derivative with 1-fluoro-1-chloroethylene using metal catalyst having chiral ligands DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-07-22 US disclosed
EP-0858992-B1 PROCESS FOR PRODUCING HALOGENATED CYCLOPROPANE DERIVATIVES DAIICHI SEIYAKU CO (JP) 2001-12-12 EP disclosed
EP-0858992-A1 PROCESS FOR PRODUCING HALOGENATED CYCLOPROPANE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1998-08-19 EP disclosed
JP-H09295963-A PRODUCTION OF D-ACETYLTHIOISOBUTYRIC ACID TOYO KASEI KOGYO CO LTD 1997-11-18 JP disclosed
EP-0435178-B1 Process for racemizing optically active carboxylic acid esters MITSUBISHI RAYON CO (JP) 1994-03-23 EP disclosed
US-5149855-A Recomposing, contacting with amine; elipdar aprotic solvent MITSUBISHI RAYON CO., LTD. (JP) 1992-09-22 US disclosed
EP-0435178-A1 Process for racemizing optically active carboxylic acid esters MITSUBISHI RAYON CO., LTD. (JP) 1991-07-03 EP disclosed
US-4411836-A HEATING IN PRESENCE OF FATTY OR AROMATIC ACID SALT OR TERTIARY AMINE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-25 US disclosed
US-4404206-A HYPOTENSIVE AND CARDIOTONIC AGENTS SCIENCE UNION ET CIE (FR) 1983-09-13 US disclosed
US-4325886-A BY FORMING A SALT WITH A DIPHENYL HYDROXY AMINE COMPOUND, FRACTIONAL CRYSTALLIZATION, SEPARATION AND ACIDIFICATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-04-20 US disclosed
US-4297282-A REACTING AN A-METHYL-B-ACYLTHIOPROPIONIC ACID WITH AN OPTICALLY ACTIVE ARYLALKYL PRIMARY AMINE; CRYSTALLIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-10-27 US disclosed