SCHEMBL3430474

SCHEMBL3430474

COC(C)(Nc1nc(N)nc(N)n1)OC

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.35
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.31
GAA P10253 2/20 0.31
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
TP53 P04637 1/20 0.30
POLB P06746 1/20 0.30
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5804830 0.81 HSD17B10 (0.36) HSD17B10SMN1; SMN2MAPTLMNA
SCHEMBL313536 0.80 MAPT (0.37) HSD17B10SMN1; SMN2MAPTGAATP53
SCHEMBL4452232 0.80 CDK1 (0.32) HSD17B10LMNAHTT
SCHEMBL9844627 0.80 CDK1 (0.31)
SCHEMBL10599233 0.77 SMN1; SMN2 (0.58) SMN1; SMN2MAPTLMNAGAAKDM4E
SCHEMBL3732341 0.74 HSD17B10 (0.31) HSD17B10
SCHEMBL668620 0.74 HSD17B10 (0.32) HSD17B10
SCHEMBL10862753 0.73 MAPT (0.38) HSD17B10SMN1; SMN2MAPTLMNAGAA
SCHEMBL6719673 0.73 MAPT (0.38) SMN1; SMN2MAPTLMNAGAAKDM4E
SCHEMBL1088645 0.72 HSD17B10 (0.30) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2249959-B1 PRODUCT GIVAUDAN SA (CH) 2016-04-13 EP disclosed
US-8357651-B2 Aminoplast microcapsules containing fragrance GIVAUDAN SA (CH) 2013-01-22 US disclosed
US-20100323938-A1 Product GIVAUDAN SA (CH) 2010-12-23 US disclosed
EP-2249959-A1 PRODUCT Givaudan SA (CH) 2010-11-17 EP disclosed
WO-2009100553-A1 PRODUCT GIVAUDAN SA (CH) 2009-08-20 WO disclosed
EP-1065227-B1 Color improvement of dimethoxyethanal-melamine resins CLARIANT FRANCE SA (FR) 2004-09-01 EP disclosed
EP-1065227-A3 Color improvement of dimethoxyethanal-melamine resins Clariant (France) S.A. (FR) 2002-07-31 EP disclosed
EP-1065227-A2 Color improvement of dimethoxyethanal-melamine resins Clariant (France) S.A. (FR) 2001-01-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100323938-A1 Product SRM, PNMT, PFAS HSD17B10 3552/4885SMN1; SMN2 1970/4885MAPT 685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.