SCHEMBL3430652

SCHEMBL3430652

O=C(OC(=O)c1ccccc1C(F)(F)F)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
GAA P10253 1/20 0.50
KCNK3 O14649 2/20 0.49
KCNK9 Q9NPC2 2/20 0.49
F2 P00734 1/20 0.44
POLB P06746 1/20 0.42
CTNNB1 P35222 1/20 0.42
WNT3A P56704 1/20 0.42
MRGPRX1 Q96LB2 1/20 0.41
TSHR P16473 1/20 0.41
CES1 P23141 1/20 0.41
CNR2 P34972 1/20 0.41
MAPK1 P28482 1/20 0.41
HIF1A Q16665 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.40
TAS2R14 Q9NYV8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1405144 0.91 LMNA (0.58) LMNAGAAKCNK3KCNK9CTNNB1
SCHEMBL20561314 0.87 KCNK3 (0.45) LMNAGAAKCNK3KCNK9F2
SCHEMBL27618282 0.87 KAT6A (0.48) LMNAGAAKCNK3KCNK9F2
SCHEMBL577104 0.82 KCNK3 (0.41) LMNAGAAKCNK3KCNK9F2
SCHEMBL322998 0.81 LMNA (0.58) LMNAF2POLBTSHRCES1
SCHEMBL6675290 0.81 LMNA (0.51) LMNAGAAKCNK3KCNK9CTNNB1
SCHEMBL10519876 0.80 LMNA (0.58) LMNAGAAKCNK3KCNK9CTNNB1
SCHEMBL29055923 0.79 LMNA (0.56) LMNAF2POLBTSHRCES1
SCHEMBL3717986 0.78 GAA (0.56) LMNAGAAKCNK3KCNK9POLB
SCHEMBL31369140 0.78 GAA (0.56) LMNAGAAKCNK3KCNK9POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079876-A Fluopicola strain method for synthesizing amide 2026-05-26 CN disclosed
EP-3635022-B1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME ETNA TEC LTD (US) 2025-05-21 EP disclosed
WO-2024010056-A1 SECONDARY BATTERY ダイキン工業株式会社 2024-01-11 WO disclosed
WO-2024010057-A1 NEGATIVE ELECTRODE, BATTERY, AND METHOD FOR COVERING BATTERY MATERIAL ダイキン工業株式会社 2024-01-11 WO disclosed
WO-2023249003-A1 SURFACE TREATMENT AGENT FOR ELECTRODE MATERIAL, POSITIVE ELECTRODE ACTIVE MATERIAL, CURRENT COLLECTOR FOIL, NEGATIVE ELECTRODE ACTIVE MATERIAL, CONDUCTIVE AID, ELECTRODE, BATTERY, METHOD FOR MANUFACTURING POSITIVE ELECTRODE ACTIVE MATERIAL, METHOD FOR MANUFACTURING CURRENT COLLECTOR FOIL, METHOD FOR MANUFACTURING NEGATIVE ELECTRODE ACTIVE MATERIAL, METHOD FOR MANUFACTURING CONDUCTIVE AID, AND METHOD FOR MANUFACTURING ELECTRODE ダイキン工業株式会社 2023-12-28 WO disclosed
WO-2023238909-A1 ELECTROLYTE SOLUTION AND SECONDARY BATTERY USING SAME ダイキン工業株式会社 2023-12-14 WO disclosed
CN-114805188-B Fluopicolide synthesis method 利民化学有限责任公司 2023-11-21 CN disclosed
CN-116354830-A Process for the preparation of functionalized fluorinated monomers, fluorinated monomers and compositions for the preparation thereof 埃特纳科技有限公司 2023-06-30 CN disclosed
WO-2023079988-A1 FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME 国立大学法人京都大学 2023-05-11 WO disclosed
CN-110770271-B Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same 埃特纳科技有限公司 2023-04-18 CN disclosed
EP-3145915-A1 ANTIDIABETIC TRICYCLIC COMPOUNDS Merck Sharp & Dohme Corp. (US) 2017-03-29 EP disclosed
WO-2015176640-A1 ANTIDIABETIC TRICYCLIC COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2015-11-26 WO disclosed
EP-1651604-B1 N-´2-(2-PYRIDINYL)ETHYL BENZAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDES BAYER SAS (FR) 2014-11-12 EP disclosed
US-7723364-B2 N-[2-(2-pyridinyl) ethyl]benzamide compounds and their use as fungicides BAYER CROPSCIENCE SA (FR) 2010-05-25 US disclosed
US-20080154049-A1 for acylation of an aromatic compound, comprising reacting an aromatic compound and an acylating agent of the carboxylic acid type, in the presence of a Lewis acid and of a silylated reagent selected from the group consisting of halosilanes and halosiloxanes. SHASUN PHARMA SOLUTIONS LIMITED (GB) 2008-06-26 US disclosed
US-20060246102-A1 N-'2-(2-pyridinyl) ethylbenzamide compounds and their use as fungicides BAYER SAS (FR) 2006-11-02 US disclosed
EP-1651604-A2 N-¬2-(2-PYRIDINYL)ETHYL|BENZAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDES Bayer CropScience S.A. (FR) 2006-05-03 EP disclosed
WO-2005014545-A2 N-′2-(2-PYRIDINYL) ETHYLBENZAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDES BAYER CROPSCIENCE S.A. (FR) 2005-02-17 WO disclosed
EP-1500651-A1 N-[2-(2-Pyridinyl)ethyl]benzamide compounds and their use as fungicides Bayer CropScience S.A. (FR) 2005-01-26 EP disclosed
US-4099014-A BLOOD PLATELET AGGREGATION INHIBITORS THE UPJOHN COMPANY (US) 1978-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246102-A1 N-'2-(2-pyridinyl) ethylbenzamide compounds and their use as fungicides CYP1A2, CYP4B1, CYP1B1 LMNA 1980/4885GAA 175/4885KCNK3 1711/4885
US-20080154049-A1 for acylation of an aromatic compound, comprising reacting an aromatic compound and an acylating agent of the carboxylic acid type, in the presence of a Lewis acid and of a silylated reagent selected from the group consisting of halosilanes and halosiloxanes. AADAC, APEH, DDC LMNA 1577/4885GAA 615/4885KCNK3 2465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.