SCHEMBL1405144

SCHEMBL1405144

O=C(OC(=O)c1ccccc1C(F)(F)F)c1ccccc1C(F)(F)F

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.58
GAA P10253 1/20 0.58
CTNNB1 P35222 3/20 0.47
WNT3A P56704 3/20 0.47
CNR2 P34972 2/20 0.46
CES2 O00748 1/20 0.46
PTGS1 P23219 1/20 0.44
KCNK3 O14649 1/20 0.44
KCNK9 Q9NPC2 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MRGPRX1 Q96LB2 1/20 0.43
NFKB1 P19838 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3430652 0.91 LMNA (0.50) LMNAGAACTNNB1WNT3ACNR2
SCHEMBL6675290 0.89 LMNA (0.51) LMNAGAACTNNB1WNT3ACNR2
SCHEMBL10519876 0.88 LMNA (0.58) LMNAGAACTNNB1WNT3ACNR2
SCHEMBL27570825 0.86 LMNA (0.56) LMNAGAACTNNB1WNT3ACNR2
SCHEMBL11074677 0.86 LMNA (0.56) LMNAGAACTNNB1WNT3ACNR2
SCHEMBL3549198 0.86 LMNA (0.49) LMNAGAACTNNB1WNT3ACNR2
SCHEMBL28799431 0.86 LMNA (0.49) LMNAGAACTNNB1WNT3ACNR2
SCHEMBL6205138 0.84 LMNA (0.47) LMNAGAACTNNB1WNT3ACNR2
SCHEMBL513905 0.84 LMNA (0.55) LMNAGAACTNNB1WNT3ACNR2
SCHEMBL45490 0.84 LMNA (0.59) LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2125931-B1 VINYL ENDS MEASURING METHOD EASTMAN CHEM CO (US) 2011-03-09 EP claimed
US-20080188003-A1 Vinyl ends method EASTMAN CHEMICAL COMPANY 2008-08-07 US claimed
CN-122079876-A Fluopicola strain method for synthesizing amide 2026-05-26 CN disclosed
EP-3635022-B1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME ETNA TEC LTD (US) 2025-05-21 EP disclosed
WO-2024010056-A1 SECONDARY BATTERY ダイキン工業株式会社 2024-01-11 WO disclosed
WO-2024010057-A1 NEGATIVE ELECTRODE, BATTERY, AND METHOD FOR COVERING BATTERY MATERIAL ダイキン工業株式会社 2024-01-11 WO disclosed
WO-2023249003-A1 SURFACE TREATMENT AGENT FOR ELECTRODE MATERIAL, POSITIVE ELECTRODE ACTIVE MATERIAL, CURRENT COLLECTOR FOIL, NEGATIVE ELECTRODE ACTIVE MATERIAL, CONDUCTIVE AID, ELECTRODE, BATTERY, METHOD FOR MANUFACTURING POSITIVE ELECTRODE ACTIVE MATERIAL, METHOD FOR MANUFACTURING CURRENT COLLECTOR FOIL, METHOD FOR MANUFACTURING NEGATIVE ELECTRODE ACTIVE MATERIAL, METHOD FOR MANUFACTURING CONDUCTIVE AID, AND METHOD FOR MANUFACTURING ELECTRODE ダイキン工業株式会社 2023-12-28 WO disclosed
WO-2023238909-A1 ELECTROLYTE SOLUTION AND SECONDARY BATTERY USING SAME ダイキン工業株式会社 2023-12-14 WO disclosed
CN-114805188-B Fluopicolide synthesis method 利民化学有限责任公司 2023-11-21 CN disclosed
CN-116354830-A Process for the preparation of functionalized fluorinated monomers, fluorinated monomers and compositions for the preparation thereof 埃特纳科技有限公司 2023-06-30 CN disclosed
WO-2023079988-A1 FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME 国立大学法人京都大学 2023-05-11 WO disclosed
US-20180334417-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ETNA-TEC, LTD. 2018-11-22 US disclosed
EP-1651604-B1 N-´2-(2-PYRIDINYL)ETHYL BENZAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDES BAYER SAS (FR) 2014-11-12 EP disclosed
EP-2125931-B1 VINYL ENDS MEASURING METHOD EASTMAN CHEM CO (US) 2011-03-09 EP disclosed
US-7723364-B2 N-[2-(2-pyridinyl) ethyl]benzamide compounds and their use as fungicides BAYER CROPSCIENCE SA (FR) 2010-05-25 US disclosed
US-20080154049-A1 for acylation of an aromatic compound, comprising reacting an aromatic compound and an acylating agent of the carboxylic acid type, in the presence of a Lewis acid and of a silylated reagent selected from the group consisting of halosilanes and halosiloxanes. SHASUN PHARMA SOLUTIONS LIMITED (GB) 2008-06-26 US disclosed
US-20060246102-A1 N-'2-(2-pyridinyl) ethylbenzamide compounds and their use as fungicides BAYER SAS (FR) 2006-11-02 US disclosed
EP-1651604-A2 N-¬2-(2-PYRIDINYL)ETHYL|BENZAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDES Bayer CropScience S.A. (FR) 2006-05-03 EP disclosed
WO-2005014545-A2 N-′2-(2-PYRIDINYL) ETHYLBENZAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDES BAYER CROPSCIENCE S.A. (FR) 2005-02-17 WO disclosed
EP-1500651-A1 N-[2-(2-Pyridinyl)ethyl]benzamide compounds and their use as fungicides Bayer CropScience S.A. (FR) 2005-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180334417-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ALKBH3, FTO, THEM6 LMNA 1217/4885GAA 2927/4885CTNNB1 2895/4885
US-20060246102-A1 N-'2-(2-pyridinyl) ethylbenzamide compounds and their use as fungicides CYP1A2, CYP4B1, CYP1B1 LMNA 1980/4885GAA 175/4885CTNNB1 4546/4885
US-20080154049-A1 for acylation of an aromatic compound, comprising reacting an aromatic compound and an acylating agent of the carboxylic acid type, in the presence of a Lewis acid and of a silylated reagent selected from the group consisting of halosilanes and halosiloxanes. AADAC, APEH, DDC LMNA 1577/4885GAA 615/4885CTNNB1 4747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.