Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11673202 | 0.87 | KMT2A (0.44) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL3674752 | 0.81 | HDAC3 (0.57) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL8860523 | 0.81 | MAPT (0.50) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL25049822 | 0.80 | MAPT (0.67) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL6571 | 0.80 | MAPT (0.67) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL28116625 | 0.79 | ESR1 (0.52) | MAPTKMT2AALDH1A1ESR1ESR2 | |
| SCHEMBL28325099 | 0.79 | MAPT (0.48) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL13770005 | 0.79 | MAPT (0.48) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL3443562 | 0.79 | MEN1 (0.54) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL7255208 | 0.79 | CYP1A2 (0.52) | MAPTKMT2ACYP2C19HIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122094943-A | Novel 1,2, 4-oxadiazoles as fungicides | — | 2026-05-26 | — | — | CN | disclosed |
| US-12637440-B2 | Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof | LG CHEM, LTD. (KR) | 2026-05-26 | — | — | US | disclosed |
| WO-2025052333-A1 | NOVEL 1,2,4-OXADIAZOLES COMPOUNDS AS FUNGICIDE | PI INDUSTRIES LTD. (IN) | 2025-03-13 | — | — | WO | disclosed |
| CN-114901653-B | Novel amide derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof | 株式会社LG化学 | 2024-11-22 | — | — | CN | disclosed |
| EP-4074701-B1 | NOVEL AMIDE DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR, AND USE THEREOF | LG CHEMICAL LTD (KR) | 2023-12-13 | — | — | EP | disclosed |
| EP-3932927-B1 | METAL COMPLEX AND COMPOSITION INCLUDING SAID METAL COMPLEX | SUMITOMO CHEMICAL CO (JP) | 2023-09-27 | — | — | EP | disclosed |
| US-11639347-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-05-02 | — | — | US | disclosed |
| US-20230127655-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230101389-A1 | NOVEL AMIDE DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR, AND USE THEREOF | LG CHEM, LTD. (KR) | 2023-03-30 | — | — | US | disclosed |
| EP-4074701-A1 | NOVEL AMIDE DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR, AND USE THEREOF | Lg Chem, Ltd. (KR) | 2022-10-19 | — | — | EP | disclosed |
| US-4453975-A | WEED CONTROL IN CROPS; ESPECIALLY RICE | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |
| EP-0061583-B1 | HERBICIDAL COMPOSITIONS CONTAINING ALPHA-ALPHA-DIMETHYL PHENYLACETANILIDES | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1984-05-02 | — | — | EP | disclosed |
| EP-0071102-A1 | Benzotriazoles, their preparation and use as medicines | Dr. Karl Thomae GmbH (DE) | 1983-02-09 | — | — | EP | disclosed |
| EP-0061583-A1 | Herbicidal compositions containing alpha-alpha-dimethyl phenylacetanilides | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1982-10-06 | — | — | EP | disclosed |
| EP-0048045-A1 | Phenyl piperazine derivatives having antiagressive activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1982-03-24 | — | — | EP | disclosed |
| US-4129704-A | Polymerization of vinyl monomers employing a diperoxyester mixture composition prepared by reacting dihydroperoxide and peroxyester forming carbonyl compounds | PENNWALT CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |
| US-4097408-A | FROM DIHYDOPEROXIDE AND CARBONYL COMPOUND, POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
| US-4005074-A | Process for cleaving an imido side chain from penicillins and cephalosporins | ELI LILLY AND COMPANY (US) | 1977-01-25 | — | — | US | disclosed |
| US-4001239-A | CEPHALOSPORIN CLEAVAGE PROCESS | ELI LILLY AND COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3994888-A | Cephalosporin cleavage process | ELI LILLY AND COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11639347-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | MAPT 4484/4885KMT2A 4313/4885CYP2C19 1915/4885 |
| US-20230101389-A1 | NOVEL AMIDE DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR, AND USE THEREOF | DGAT2, DGAT1, MOGAT2 | MAPT 1900/4885KMT2A 572/4885CYP2C19 1759/4885 |
| US-20230127655-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | MAPT 4484/4885KMT2A 4313/4885CYP2C19 1915/4885 |
| US-12637440-B2 | Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof | DGAT2, DGAT1, DLAT | MAPT 4369/4885KMT2A 738/4885CYP2C19 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.