Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 3/20 | 0.77 |
| ▸ | KDM4A | O75164 | 2/20 | 0.70 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329669 | 0.98 | CHKA (0.81) | CHKAKDM4AKDM2AKMT2AMEN1 | |
| SCHEMBL17817509 | 0.98 | CHKA (0.81) | CHKAKDM4AKDM2AKMT2AMEN1 | |
| Fluoride Ion SCHEMBL21758528 | 0.98 | CHKA (0.74) | CHKAKDM4AKDM2AKMT2AMEN1 | |
| SCHEMBL17817506 | 0.98 | CHKA (0.81) | CHKAKDM4AKDM2AKMT2AMEN1 | |
| SCHEMBL1108055 | 0.98 | CHKA (0.81) | CHKAKDM4AKDM2AKMT2AMEN1 | |
| SCHEMBL23016755 | 0.98 | CHKA (0.81) | CHKAKDM4AKDM2AKMT2AMEN1 | |
| Fluoride Ion SCHEMBL21758539 | 0.96 | CHKA (0.78) | CHKAKDM4AKDM2AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6115401 | 0.96 | CHKA (0.78) | CHKAKDM4AKDM2AKMT2AMEN1 | |
| Bromide SCHEMBL3039129 | 0.96 | CHKA (0.85) | CHKAKDM4AKDM2AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9328425 | 0.96 | CHKA (0.78) | CHKAKDM4AKDM2AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9109238-B2 | Synthesis of diester-based lubricants from enzymatically-directed epoxides | CHEVRON U.S.A. INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-20150140623-A1 | Synthesis of Diester-Based Lubricants from Enzymatically-Directed Epoxides | NOVOZYMES A/S (DK) | 2015-05-21 | — | — | US | disclosed |
| WO-2010056832-A2 | SYNTHESIS OF DIESTER-BASED LUBRICANTS FROM ENZYMATICALLY-DIRECTED EPOXIDES | CHEVRON U.S.A. INC. (US) | 2010-05-20 | — | — | WO | disclosed |
| US-20100120642-A1 | SYNTHESIS OF DIESTER-BASED LUBRICANTS FROM ENZYMATICALLY-DIRECTED EPOXIDES | CHEVRON U.S.A. INC. (US) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150140623-A1 | Synthesis of Diester-Based Lubricants from Enzymatically-Directed Epoxides | DGAT2, ADH1A, ELOVL1 | CHKA 950/4885KDM4A 2029/4885KDM2A 2349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.