Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 12/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26616883 | 0.78 | MTNR1B (0.57) | MTNR1BMTNR1ATHRBTSHRALDH1A1 | |
| SCHEMBL23771228 | 0.78 | THRB (0.58) | MTNR1BMTNR1ATHRBTSHRALDH1A1 | |
| SCHEMBL6274304 | 0.78 | MTNR1B (0.57) | MTNR1BMTNR1ATHRBTSHRALDH1A1 | |
| SCHEMBL171425 | 0.77 | MTNR1A (0.79) | MTNR1BMTNR1ATSHRALDH1A1TP53 | |
| SCHEMBL29875454 | 0.77 | MTNR1A (0.79) | MTNR1BMTNR1ATSHRALDH1A1TP53 | |
| SCHEMBL29564854 | 0.77 | SYK (0.59) | MTNR1BMTNR1ATHRBTSHRALDH1A1 | |
| SCHEMBL11843110 | 0.77 | HSD17B10 (0.52) | MTNR1BMTNR1ATHRBTSHRALDH1A1 | |
| SCHEMBL631776 | 0.77 | KCNH3 (0.64) | MTNR1BMTNR1ATHRBTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL29564676 | 0.76 | SYK (0.58) | MTNR1BTHRBTSHRALDH1A1TP53 | |
| SCHEMBL11202583 | 0.76 | THRB (0.59) | MTNR1BMTNR1ATHRBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267836-A1 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES | UNIVERSITA DEGLI STUDI DI MILANO (IT) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267836-A1 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES | HCRTR1, HCRTR2, MTNR1A | MTNR1B 5/4885MTNR1A 3/4885THRB 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.