Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.58 |
| ▸ | DDO | Q99489 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359995 | 0.76 | DAO (0.58) | DAODDOSRC | |
| SCHEMBL3433397 | 0.75 | DAO (0.67) | DAODDOLMNA | |
| SCHEMBL3423807 | 0.74 | DAO (1.00) | DAODDO | |
| SCHEMBL22408216 | 0.74 | LMNA (0.52) | TP53SMN1; SMN2LMNA | |
| SCHEMBL9389319 | 0.73 | GRIN2D (0.56) | DAODDOSMN1; SMN2LMNA | |
| SCHEMBL8872288 | 0.72 | GRIN2D (0.50) | DAODDOSMN1; SMN2SRC | |
| SCHEMBL3421507 | 0.72 | DAO (0.58) | DAODDO | |
| SCHEMBL8873379 | 0.72 | GRIN1 (0.51) | DAOSRC | |
| SCHEMBL7350621 | 0.72 | DAO (0.65) | DAOLMNA | |
| SCHEMBL5973771 | 0.72 | GRIN1 (0.68) | SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | claimed |