Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 12/20 | 0.58 |
| ▸ | DDO | Q99489 | 5/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361286 | 0.81 | DAO (0.60) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3361624 | 0.79 | DAO (0.58) | DAODDOHRH4 | |
| SCHEMBL2310258 | 0.79 | KDM4E (0.51) | HRH4IDH1HSD17B10 | |
| SCHEMBL17603345 | 0.78 | GRIA1 (0.42) | DAODDOHRH4IDH1GRIN2D | |
| SCHEMBL3434396 | 0.76 | DAO (0.47) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3395947 | 0.76 | DAO (0.47) | DAODDOIDH1 | |
| SCHEMBL14127307 | 0.75 | CNR2 (0.46) | HRH4IDH1 | |
| SCHEMBL21734885 | 0.74 | HRH4 (0.39) | HRH4IDH1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL16767856 | 0.74 | DAO (1.00) | DAODDOHSD17B10 | |
| SCHEMBL14115020 | 0.74 | HRH4 (0.45) | HRH4IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | claimed |