Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CBLB | Q13191 | 2/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20582243 | 0.98 | ACHE (0.39) | ACHEALDH1A1KMT2AATMZDHHC20 | |
| Hydrochloric Acid SCHEMBL27998931 | 0.89 | ACHE (0.47) | ACHEALDH1A1ATMZDHHC20ZDHHC2 | |
| SCHEMBL23803153 | 0.87 | ACHE (0.48) | ACHEALDH1A1KMT2AATMZDHHC20 | |
| Bromide SCHEMBL28118433 | 0.86 | ACHE (0.47) | ACHEALDH1A1ZDHHC20ZDHHC2EGFR | |
| Hydrochloric Acid SCHEMBL233973 | 0.82 | APEX1 (0.41) | ACHEALDH1A1KMT2AATMZDHHC20 | |
| SCHEMBL5594915 | 0.81 | CNR1 (0.51) | ZDHHC20ZDHHC2CNR1CNR2 | |
| SCHEMBL1628096 | 0.80 | APEX1 (0.42) | ACHEALDH1A1KMT2AATMZDHHC20 | |
| SCHEMBL25544701 | 0.80 | APEX1 (0.42) | ACHEALDH1A1KMT2AATMZDHHC20 | |
| SCHEMBL9111857 | 0.80 | ZDHHC20 (0.50) | ACHEALDH1A1ZDHHC20ZDHHC2EGFR | |
| SCHEMBL19261723 | 0.80 | ZDHHC20 (0.50) | ACHEALDH1A1ZDHHC20ZDHHC2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110366430-A | Biocompatible and hydrophilic polymer conjugates for targeted delivery of agents | 联邦科学和工业研究组织 | 2019-10-22 | — | — | CN | claimed |
| CN-110177816-A | Copolymers and their use in detergent compositions | 科莱恩国际有限公司 | 2019-08-27 | — | — | CN | claimed |
| CN-110088397-A | polymer composition and use thereof | 凯米罗总公司 | 2019-08-02 | — | — | CN | claimed |
| CN-110088259-A | Detergent compositions containing copolymers | 科莱恩国际有限公司 | 2019-08-02 | — | — | CN | claimed |
| CN-110072818-A | Make the method for the sludge dewatering from paper pulp, Paper or cardboard manufacturing process | 凯米罗总公司 | 2019-07-30 | — | — | CN | claimed |
| CN-110023472-A | COPOLYMERS AND THEIR USE IN DETERGENT COMPOSITIONS | 科莱恩国际有限公司 | 2019-07-16 | — | — | CN | claimed |
| CN-109996858-A | Cleaning agent composition containing copolymer | 科莱恩国际有限公司 | 2019-07-09 | — | — | CN | claimed |
| CN-109983110-A | Machine dishwashing detergent comprising copolymer | 科莱恩国际有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109983177-A | Polymer is during manufacturing Paper or cardboard for controlling the purposes of deposit formation | 凯米罗总公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109715884-A | Paper product and the method for increasing its intensity | 凯米罗总公司 | 2019-05-03 | — | — | CN | claimed |
| CN-110366430-A | Biocompatible and hydrophilic polymer conjugates for targeted delivery of agents | 联邦科学和工业研究组织 | 2019-10-22 | — | — | CN | disclosed |
| CN-110177816-A | Copolymers and their use in detergent compositions | 科莱恩国际有限公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-110088259-A | Detergent compositions containing copolymers | 科莱恩国际有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-110088397-A | polymer composition and use thereof | 凯米罗总公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-110072818-A | Make the method for the sludge dewatering from paper pulp, Paper or cardboard manufacturing process | 凯米罗总公司 | 2019-07-30 | — | — | CN | disclosed |
| US-8187500-B2 | Biphasic inks | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-05-29 | — | — | US | disclosed |
| US-20100096596-A1 | BIPHASIC INKS | NATIONAL SCIENCE FOUNDATION | 2010-04-22 | — | — | US | disclosed |
| EP-0800540-A4 | HOMOGENEOUS TERPOLYMERS OF VINYL PYRROLIDONE, A QUATERNARY AMMONIUM MONOMER AND A HYDROPHOBIC MONOMER | ISP INVESTMENTS INC (US) | 1998-12-09 | — | — | EP | disclosed |
| EP-0800540-A1 | HOMOGENEOUS TERPOLYMERS OF VINYL PYRROLIDONE, A QUATERNARY AMMONIUM MONOMER AND A HYDROPHOBIC MONOMER | ISP INVESTMENTS INC. (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020227-A1 | HOMOGENEOUS TERPOLYMERS OF VINYL PYRROLIDONE, A QUATERNARY AMMONIUM MONOMER AND A HYDROPHOBIC MONOMER | ISP INVESTMENTS INC. (US) | 1996-07-04 | — | — | WO | disclosed |