SCHEMBL343278

SCHEMBL343278

Nc1cc(S(=O)(=O)O)c2ccccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
HSD17B10 Q99714 3/20 0.49
ATIC P31939 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
ALOX15 P16050 1/20 0.49
CYP2C19 P33261 1/20 0.49
HIF1A Q16665 1/20 0.49
TTR P02766 1/20 0.47
SUMO2 P61956 3/20 0.46
SUMO1 P63165 3/20 0.46
SENP7 Q9BQF6 3/20 0.46
SENP2 Q9HC62 3/20 0.46
SENP1 Q9P0U3 2/20 0.46
TDP1 Q9NUW8 4/20 0.46
MAPT P10636 2/20 0.46
RECQL P46063 2/20 0.46
KDM4E B2RXH2 1/20 0.46
NSD2 O96028 1/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29215781 0.85 CASP6 (0.57) ALDH1A1HSD17B10ATICCYP2C9ALOX15
SCHEMBL6559611 0.81 NT5E (0.57) ALDH1A1HSD17B10ATICCYP2C9ALOX15
SCHEMBL8109631 0.80 CASP6 (0.61) ALDH1A1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL29516390 0.79 PLAU (0.56) ALDH1A1HSD17B10ATICALOX15HIF1A
SCHEMBL342865 0.79 PLAU (0.56) ALDH1A1HSD17B10ATICALOX15HIF1A
SCHEMBL147723 0.79 TTR (0.65) ALDH1A1HSD17B10ATICCYP1A2TTR
SCHEMBL30091340 0.79 TTR (0.65) ALDH1A1HSD17B10ATICCYP1A2TTR
SCHEMBL29459902 0.79 TTR (0.65) ALDH1A1HSD17B10ATICCYP1A2TTR
SCHEMBL4649650 0.79 ALDH1A1 (0.52) ALDH1A1HSD17B10ATICCYP2C9CYP2C19
SCHEMBL11596773 0.78 CASP6 (0.46) ALDH1A1HSD17B10CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3724251-B2 IONICALLY HYDROPHILIZED POLYISOCYANATES, WATER CONTENT COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-11-22 EP claimed
EP-3851472-B1 IONICALLY HYDROPHILIZED POLYISOCYANATES, WATER CONTENT COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-07 EP claimed
CN-112041369-B Ionically hydrophilicized polyisocyanates, water content 科思创知识产权两合公司 2022-11-29 CN claimed
US-11365277-B2 Ionically hydrophilized polyisocyanates, water content COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2022-06-21 US claimed
EP-3875513-A1 IONICALLY HYDROPHILIZED POLYISOCYANATES AND RADICAL SCAVENGER AND/OR PEROXIDE DECOMPOSITION AGENT Covestro Intellectual Property GmbH & Co. KG (DE) 2021-09-08 EP claimed
EP-3851472-A1 IONICALLY HYDROPHILIZED POLYISOCYANATES, WATER CONTENT Covestro Intellectual Property GmbH & Co. KG (DE) 2021-07-21 EP claimed
US-20210171698-A1 IONICALLY HYDROPHILIZED POLYISOCYANATES, WATER CONTENT COVESTRO DEUTSCHLAND AG (DE) 2021-06-10 US claimed
EP-3560976-B1 IONICALLY HYDROPHILIZED POLYISOCYANATES AND RADICAL SCAVENGER AND/OR PEROXIDE DECOMPOSITION AGENT COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2021-05-26 EP claimed
EP-3724251-B1 IONICALLY HYDROPHILIZED POLYISOCYANATES, WATER CONTENT COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2021-04-07 EP claimed
CN-112041369-A Ionically hydrophilicized polyisocyanates, water content 科思创知识产权两合公司 2020-12-04 CN claimed
US-9215813-B2 Method for recycling of obsolete printed circuit boards ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2015-12-15 US claimed
EP-2170971-B1 WATER-DISPERSIBLE POLYISOCYANATES BASF SE (DE) 2011-02-02 EP claimed
US-20100183883-A1 WATER-DISPERSIBLE POLYISOCYANATES BASF SE (DE) 2010-07-22 US claimed
CN-101754990-A Water-dispersible polyisocyanates BASF SE 2010-06-23 CN claimed
EP-2170971-A1 WATER-DISPERSIBLE POLYISOCYANATES BASF SE (DE) 2010-04-07 EP claimed
WO-2009010469-A1 WATER-DISPERSIBLE POLYISOCYANATES BASF SE (DE) 2009-01-22 WO claimed
EP-1648362-A2 FILM COMPRISING THERAPEUTIC AGENTS Maibach, Todd (US) 2006-04-26 EP claimed
WO-2005004989-A2 FILM COMPRISING THERAPEUTIC AGENTS MAIBACH TODD (US) 2005-01-20 WO claimed
US-20040260119-A1 Preparation of 3-alkoxy-2-methylbenzoic acids LANXESS DEUTSCHLAND GMBH (DE) 2004-12-23 US claimed
US-20020111528-A1 Method for recombining soil AKAE YUKOH (JP) 2002-08-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040260119-A1 Preparation of 3-alkoxy-2-methylbenzoic acids TET2, ALKBH2, ALKBH3 ALDH1A1 514/4885HSD17B10 580/4885ATIC 1165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.