Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2067352 | 0.78 | MAPT (0.59) | KDM4EMAPTHSD17B10HTTHPGD | |
| SCHEMBL19829473 | 0.67 | SLC9A1 (0.50) | KDM4EMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2069427 | 0.67 | MAPT (0.47) | CACNA2D1KDM4EMAPTHSD17B10HTT | |
| SCHEMBL30547571 | 0.66 | MAPK6 (0.38) | KDM4EMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL26908029 | 0.66 | MAPK6 (0.38) | KDM4EMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL31423 | 0.64 | NQO1 (0.74) | KDM4EMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL26503115 | 0.64 | NPSR1 (0.39) | KDM4EHPGDL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL14456522 | 0.64 | RXRA (0.48) | KDM4EMAPTL3MBTL1NPC1 | |
| SCHEMBL14400496 | 0.63 | RXRA (0.60) | — | |
| Hydrochloric Acid SCHEMBL29769999 | 0.63 | RAB9A (0.39) | KDM4EMAPTHSD17B10HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2182805-A2 | ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVIRUS INFECTION | Siga Technologies, Inc. (US) | 2010-05-12 | — | — | EP | claimed |
| WO-2009029622-A2 | ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVIRUS INFECTION | SIGA TECHNOLOGIES, INC. (US) | 2009-03-05 | — | — | WO | claimed |
| EP-2182805-A2 | ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVIRUS INFECTION | Siga Technologies, Inc. (US) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009029622-A2 | ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVIRUS INFECTION | SIGA TECHNOLOGIES, INC. (US) | 2009-03-05 | — | — | WO | disclosed |