Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.39 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434266 | 0.93 | PGR (0.39) | ALDH1A1KDM4EPGRCHRNA7PTGS1 | |
| SCHEMBL3431941 | 0.91 | ALDH1A1 (0.45) | ALDH1A1KDM4EHTTMEN1MAPT | |
| SCHEMBL3434352 | 0.90 | RPA1 (0.39) | ALDH1A1KDM4EMEN1MAPTMAPK1 | |
| SCHEMBL3434336 | 0.90 | RXRA (0.40) | ALDH1A1KDM4EHTTMEN1MAPT | |
| SCHEMBL1110649 | 0.90 | ALDH1A1 (0.44) | ALDH1A1KDM4EHTTMEN1MAPT | |
| SCHEMBL3431428 | 0.89 | RXRA (0.47) | ALDH1A1KDM4EHTTMEN1MAPT | |
| SCHEMBL3428695 | 0.89 | ALDH1A1 (0.44) | ALDH1A1KDM4EHTTMEN1MAPT | |
| SCHEMBL3434328 | 0.88 | PGR (0.38) | ALDH1A1KDM4EPGRSMN1; SMN2RXRA | |
| SCHEMBL3434465 | 0.87 | ALDH1A1 (0.44) | ALDH1A1KDM4EHTTMEN1MAPT | |
| SCHEMBL3434215 | 0.87 | PGR (0.44) | MEN1KMT2APGRSLC16A3SLC16A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254885-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |