Carbamic Acid

Carbamic Acid

SCHEMBL3434151

Cn1cnc2ccc(C(=O)c3cccs3)cc21.NC(=O)O

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.51
RAB9A P51151 5/20 0.51
HPGD P15428 4/20 0.45
HTT P42858 2/20 0.45
HPGDS O60760 1/20 0.44
CHEK2 O96017 1/20 0.43
CYP2C9 P11712 3/20 0.43
MAPT P10636 3/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 2/20 0.43
TSHR P16473 2/20 0.43
ABL1 P00519 2/20 0.43
TP53 P04637 2/20 0.43
GMNN O75496 1/20 0.43
TUBB4A P04350 1/20 0.43
CYP1A2 P05177 1/20 0.43
TUBB P07437 1/20 0.43
TUBA3C P0DPH7 1/20 0.43
NFKB1 P19838 1/20 0.43
MAOA P21397 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL3412931 0.82 ALDH1A1 (0.50) RAB9AHPGDHTTALDH1A1ABL1
SCHEMBL11171 0.76 SMN1; SMN2 (0.50) NPC1RAB9AHPGDCHEK2MAPT
SCHEMBL1869730 0.74 FGFR1 (0.60) NPC1RAB9AHPGDMAPTALDH1A1
Carbamic Acid SCHEMBL4557190 0.73 HTT (0.61) NPC1RAB9AHPGDHTTHPGDS
SCHEMBL5696324 0.73 NPC1 (0.49) NPC1RAB9AHPGDHTTHPGDS
SCHEMBL16602284 0.72 ALDH1A1 (0.53) NPC1RAB9AHPGDHTTMAPT
SCHEMBL29819602 0.72 ALDH1A1 (0.53) NPC1RAB9AHPGDHTTMAPT
SCHEMBL7362182 0.70 F10 (0.49) NPC1RAB9AHPGDTP53KMT2A
SCHEMBL20570515 0.70 CHRNA7 (0.47) NPC1RAB9AHPGDMAPTALDH1A1
Carbamic Acid SCHEMBL1758683 0.70 EGLN3 (0.53) NPC1HPGDHTTMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2133318-B1 Building board NICHIHA KK (JP) 2010-12-22 EP disclosed
US-20090191251-A1 ANTIMICROBIAL MOLDED ARTICLE, LAMINATE, HEAT INSULATING MATERIAL AND SYNTHETIC LEATHER PRODUCT FUKATSU FUMIOKI 2009-07-30 US disclosed
US-7534485-B2 Building board NICHIHA CORPORATION (JP) 2009-05-19 US disclosed
US-20080233160-A1 Building board NICHIHA CORPORATION 2008-09-25 US disclosed
US-20080138385-A1 Antibacterial Composition, Antibacterial Molding, Solution Containing Antibacterial Composition, Detergent, Surface of Tatami Mat and Tatami Mat IDEMITSU TECHNOFINE CO., LTD. (JP) 2008-06-12 US disclosed
EP-1779727-A1 ANTIBACTERIAL COMPOSITION, ANTIBACTERIAL MOLDING, SOLUTION CONTAINING ANTIBACTERIAL COMPOSITION, DETERGENT, SURFACE OF TATAMI MAT AND TATAMI MAT Idemitsu Technofine Co. Ltd (JP) 2007-05-02 EP disclosed
CN-1239768-C Molded antimicrobial article, and production process thereof TORAY INDUSTRIES (JP) 2006-02-01 CN disclosed
CN-1239162-A Molded antimicrobial article, and production process thereof TORAY INDUSTRIES (JP) 1999-12-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138385-A1 Antibacterial Composition, Antibacterial Molding, Solution Containing Antibacterial Composition, Detergent, Surface of Tatami Mat and Tatami Mat TPMT, KAT5, CARM1 NPC1 3166/4885RAB9A 4068/4885HPGD 3744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.