SCHEMBL3434665

SCHEMBL3434665

O=C1CCC(c2ccccc2S(=O)(=O)O)CCO1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.35
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
HTR6 P50406 3/20 0.31
LMNA P02545 1/20 0.31
CA1 P00915 2/20 0.31
TSHR P16473 1/20 0.31
CA9 Q16790 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9097473 0.79 HSD11B1 (0.48) HSD11B1MAOAMAOBHTR6LMNA
SCHEMBL29219511 0.79 HSD11B1 (0.48) HSD11B1MAOAMAOBHTR6LMNA
SCHEMBL2040982 0.76 F2 (0.37) HSD11B1MAOAMAOB
SCHEMBL4279326 0.75 PTGS2 (0.46) HSD11B1LMNATSHR
SCHEMBL27952944 0.73 PTGS2 (0.45) HSD11B1LMNATSHR
SCHEMBL777774 0.72 HSD11B1 (0.46) HSD11B1MAOAMAOBHTR6LMNA
SCHEMBL664311 0.72 SRD5A1 (0.45)
SCHEMBL5069252 0.71 HSD11B1 (0.35) HSD11B1MAOAMAOBLMNA
SCHEMBL9099602 0.70 HSD11B1 (0.38) HSD11B1MAOAMAOBLMNACA1
SCHEMBL9098609 0.70 HSD11B1 (0.41) HSD11B1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9080012-B2 One-pot, neat ring opening polymerization to prepare resin XEROX CORPORATION (US) 2015-07-14 US claimed
US-9000101-B2 Anhydride end-capping of polymers XEROX CORPORATION (US) 2015-04-07 US claimed
US-8975344-B2 Polyester/polycarbonate block copolymers via one-pot, neat ring opening polymerization XEROX CORPORATION (US) 2015-03-10 US claimed
EP-2267054-B1 Polyester synthesis XEROX CORP (US) 2012-08-22 EP claimed
EP-2267054-A1 Polyester synthesis Xerox Corporation (US) 2010-12-29 EP claimed
US-20100304287-A1 POLYESTER SYNTHESIS XEROX CORPORATION (US) 2010-12-02 US claimed
US-9080012-B2 One-pot, neat ring opening polymerization to prepare resin XEROX CORPORATION (US) 2015-07-14 US disclosed
US-9000101-B2 Anhydride end-capping of polymers XEROX CORPORATION (US) 2015-04-07 US disclosed
US-8975344-B2 Polyester/polycarbonate block copolymers via one-pot, neat ring opening polymerization XEROX CORPORATION (US) 2015-03-10 US disclosed
EP-2267054-B1 Polyester synthesis XEROX CORP (US) 2012-08-22 EP disclosed
EP-2267054-A1 Polyester synthesis Xerox Corporation (US) 2010-12-29 EP disclosed
US-20100304287-A1 POLYESTER SYNTHESIS XEROX CORPORATION (US) 2010-12-02 US disclosed