Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5070897 | 0.82 | PKM (0.37) | HSD11B1ALDH1A1MEN1KMT2AMYC | |
| SCHEMBL5959061 | 0.81 | CNR2 (0.38) | CNR2LMNAMAPK1 | |
| SCHEMBL5068917 | 0.81 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL5068380 | 0.81 | KDM4E (0.36) | HSD11B1 | |
| SCHEMBL8368970 | 0.79 | HSD11B1 (0.41) | HSD11B1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL29000468 | 0.77 | HTR2A (0.39) | HSD11B1ALDH1A1SMN1; SMN2MEN1GAA | |
| SCHEMBL9099602 | 0.77 | HSD11B1 (0.38) | HSD11B1SMN1; SMN2MEN1KMT2AMYC | |
| SCHEMBL9097473 | 0.76 | HSD11B1 (0.48) | HSD11B1SMN1; SMN2MYCMAOAMAOB | |
| SCHEMBL29219511 | 0.76 | HSD11B1 (0.48) | HSD11B1SMN1; SMN2MYCMAOAMAOB | |
| SCHEMBL2040982 | 0.76 | F2 (0.37) | HSD11B1MEN1KMT2AMYCMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365215-B2 | Process for preparing 4-aminotetrahydropyran compound and an acid salt thereof, synthetic intermediate thereof and process for preparing the same | UBE INDUSTRIES, LTD. (JP) | 2008-04-29 | — | — | US | disclosed |
| US-20070106083-A1 | Process for preparing 4-aminotetrahydropyran compound and an acid salt thereof, synthetic intermediate thereof and process for preparing the same | UBE INDUSTRIES, LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| EP-1661894-A1 | PROCESS FOR PRODUCTION OF 4-AMINOTETRAHYDROPYRANS AND SALTS THEREOF WITH ACIDS, INTERMEDIATES FOR THE PROCESS, AND PROCESS FOR PRODUCTION THEREOF | Ube Industries, Ltd. (JP) | 2006-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070106083-A1 | Process for preparing 4-aminotetrahydropyran compound and an acid salt thereof, synthetic intermediate thereof and process for preparing the same | PAH, HPD, REN | HSD11B1 220/4885ALDH1A1 875/4885SMN1; SMN2 3594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.