Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 2/20 | 0.46 |
| ▸ | NR1D2 | Q14995 | 1/20 | 0.44 |
| ▸ | TAF1 | P21675 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434754 | 0.78 | NMT1 (0.51) | NMT1NR1D2TAF1ACP1CARM1 | |
| SCHEMBL1363925 | 0.78 | NMT1 (0.51) | NMT1NR1D2TAF1ACP1CARM1 | |
| SCHEMBL19547078 | 0.73 | NR1D2 (0.46) | NMT1NR1D2TAF1CARM1PRMT6 | |
| SCHEMBL12140976 | 0.72 | MEP1B (0.48) | NMT1NR1D2TAF1 | |
| SCHEMBL17196558 | 0.72 | AGXT (0.46) | CASR | |
| SCHEMBL17345718 | 0.72 | AGXT (0.50) | PRMT6HTR1ACASR | |
| SCHEMBL17775505 | 0.72 | AGXT (0.46) | CASR | |
| SCHEMBL1364691 | 0.70 | NMT1 (0.52) | NMT1 | |
| SCHEMBL11363491 | 0.69 | FAAH (0.50) | NMT1NR1D2TAF1CARM1PRMT6 | |
| SCHEMBL26324335 | 0.68 | CASR (0.47) | PRMT6HTR1ACASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247184-A1 | DUAL PHARMACOPHORES-PDE4-MUSCARINIC ANTAGONISTICS | Glaxo Group Limited (GB) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009100167-A1 | DUAL PHARMACOPHORES-PDE4-MUSCARINIC ANTAGONISTICS | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |