Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3432814 | 0.93 | ALDH1A1 (0.38) | RPA1RXFP1MCHR1KDM4EMEN1 | |
| SCHEMBL3434352 | 0.90 | RPA1 (0.39) | RPA1RXFP1BRD9RXRARXRB | |
| SCHEMBL3433402 | 0.90 | CNR2 (0.38) | RPA1MCHR1FAAHMGLLCNR2 | |
| SCHEMBL1110649 | 0.90 | ALDH1A1 (0.44) | RPA1FAAHCNR2ADORA2ASLC16A3 | |
| SCHEMBL3427610 | 0.89 | RPA1 (0.45) | RPA1RXFP1ARFAAHMGLL | |
| SCHEMBL3436334 | 0.88 | CNR2 (0.43) | RPA1FAAHMGLLCNR2ADORA2A | |
| SCHEMBL3430605 | 0.88 | RXFP1 (0.43) | RPA1RXFP1FAAHBRD9ALDH1A1 | |
| SCHEMBL3434465 | 0.87 | ALDH1A1 (0.44) | RPA1SLC16A3SLC16A1MCTS1RXRA | |
| SCHEMBL3434918 | 0.86 | ALDH1A1 (0.40) | RPA1FAAHMGLLSLC16A3SLC16A1 | |
| SCHEMBL1765280 | 0.85 | CHRNA7 (0.50) | RPA1RXFP1FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254885-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |