Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19849802 | 0.95 | PKM (0.63) | PKMRAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL19844152 | 0.93 | RAB9A (0.54) | PKMRAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL3434351 | 0.90 | RAB9A (0.69) | PKMRAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL3434885 | 0.88 | RAB9A (0.58) | PKMRAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL27691343 | 0.86 | HRH3 (0.64) | PKMRAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL2853034 | 0.86 | TDP1 (0.66) | PKMRAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL10723995 | 0.86 | ESR1 (0.60) | PKMRAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL25694627 | 0.85 | HRH3 (0.48) | PKMRAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL11323600 | 0.85 | PKM (0.77) | PKMRAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL18538485 | 0.84 | MAPT (0.55) | PKMRAB9AMAPTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957223-B2 | Bis(aryloxyalkyl) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-9957223-B2 | Bis(aryloxyalkyl) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-20180037535-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | FIRST NATIONAL BANK OF PENNSYLVANIA | 2018-02-08 | — | — | US | disclosed |
| US-20180037535-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | FIRST NATIONAL BANK OF PENNSYLVANIA | 2018-02-08 | — | — | US | disclosed |
| US-20120100323-A1 | Novel bis(ARYLOXYALKYL) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS, LLC | 2012-04-26 | — | — | US | disclosed |
| US-20120100323-A1 | Novel bis(ARYLOXYALKYL) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS, LLC | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037535-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | AHR, AR, ARNT | PKM 2688/4885RAB9A 3399/4885MAPT 4091/4885 |
| US-20120100323-A1 | Novel bis(ARYLOXYALKYL) esters of aromatic polycarboxylic acids and method of preparation | AHR, AR, ARNT | PKM 2688/4885RAB9A 3399/4885MAPT 4091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.